Angiopep-2 hydrochloride|西域试剂

Angiopep-2 hydrochloride,99.30%

产品编号：Bellancom-P2341| 分子式：C₁₀₄H₁₅₀ClN₂₉O₃₁| 分子量：2337.93

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
Bellancom-P2341		￥1400.00	杭州北京（现货）
Bellancom-P2341		￥4000.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

Angiopep-2 hydrochloride

产品介绍

Angiopep-2 hydrochloride 是脑肽载体。抗肿瘤活性分子与 Angiopep-2 肽载体的结合可提高其在脑癌中的活性.

生物活性

Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer.

体外研究

Paclitaxel is conjugated to a brain peptide vector, Angiopep-2, to provide a paclitaxel– Angiopep-2 conjugate named ANG1005. ANG1005 enters the brain to a greater extent than paclitaxel and bypasses the P-gp. ANG1005 has an antineoplastic potency similar to that of paclitaxel against human cancer cell lines.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

ANG1005 administration leads to a significant increase in the survival of mice with intracerebral implantation of U87 MG glioblastoma cells or NCI-H460 lung carcinoma cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

ANG1005 administration leads to a significant increase in the survival of mice with intracerebral implantation of U87 MG glioblastoma cells or NCI-H460 lung carcinoma cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

H₂O : 100 mg/mL (42.77 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.4277 mL	2.1386 mL	4.2773 mL
5 mM	0.0855 mL	0.4277 mL	0.8555 mL
10 mM	0.0428 mL	0.2139 mL	0.4277 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶