iRGD peptide 1 TFA,98.45%

产品编号:Bellancom-P0122B| 分子式:C37H60F3N13O16S2| 分子量:1064.08

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货号 包装 价格 库存与货期 购买量 操作
Bellancom-P0122B
600.00 杭州 北京(现货)
Bellancom-P0122B
1500.00 杭州 北京(现货)
Bellancom-P0122B
2400.00 杭州 北京(现货)

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iRGD peptide 1 TFA

产品介绍 iRGD peptide 1 TFA 是一种原型肿瘤特异性组织穿透肽,可将活性分子深深地输送到血管外肿瘤组织中,并具有抗转移活性。
生物活性

iRGD peptide 1 TFA is the prototypic tumor-specific tissue-penetrating peptide, which delivers agents deep into extravascular tumor tissue. iRGD peptide 1 TFA has anti-metastatic activity.

体外研究

iRGD peptide 1 (iRGD) inhibits migration of tumor cells and caused chemorepulsion in vitro in a CendR- and NRP-1-dependent manner. iRGD peptide 1 induces dramatic collapse of cellular processes and partial cell detachment, resulting in the repellent activity. These effects are prominently displayed when the cells are seeded on fibronectin, suggesting a role of CendR in functional regulation of integrins.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

iRGD peptide 1 (amino acid sequence: CRGDKGPDC; 4 μmol/kg; intravenous injection; every other day; for 21 days) potently inhibits spontaneous metastasis in mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

iRGD peptide 1 (amino acid sequence: CRGDKGPDC; 4 μmol/kg; intravenous injection; every other day; for 21 days) potently inhibits spontaneous metastasis in mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状Solid
溶解性数据
In Vitro: 

H2O : ≥ 100 mg/mL (93.98 mM)

* "≥" means soluble, but saturation unknown.

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.9398 mL 4.6989 mL 9.3978 mL
5 mM 0.1880 mL 0.9398 mL 1.8796 mL
10 mM 0.0940 mL 0.4699 mL 0.9398 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献

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