Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA MOG (35-55 (TFA))|西域试剂

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA MOG (35-55 (TFA)),99.90%

产品编号：Bellancom-P1240A| 分子式：C₁₂₀H₁₇₈F₃N₃₅O₃₁S| 分子量：2695.97

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货号	价格	库存与货期
Bellancom-P1240A	￥1500.00	杭州北京（现货）
Bellancom-P1240A	￥4500.00	杭州北京（现货）
Bellancom-P1240A	￥7600.00	杭州北京（现货）

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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA MOG (35-55 (TFA))

产品介绍

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) TFA 是中枢神经鞘的一个次要成分。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA 有致脑炎活性，诱导 T 细胞增殖。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA 诱导 Th1 细胞因子反应以及相对高水平的 IgG 抗体产生。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA 引发复发缓解性神经系统疾病，伴有广泛的斑块样脱髓鞘。

生物活性

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) TFA is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA produces a relapsing-remitting neurological disease with extensive plaque-like demyelination.

体外研究

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 0-50 μg/mL; 72 h; lymph nodes cells) TFA induces T cell proliferative and secretes Th1 cytokines including IFN-γ, TNF-α, IL-10, IL-4 and IL-5. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA increases the level of IgG.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 200 μg (0.2 mL); i.p.; once, for 38 d) TFA has encephalitogenic activity in HLA-DR2 (DRB1*1501) mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	HLA-DR2 (DRB1*1501) mice
Dosage:	200 μg (0.2 mL)
Administration:	Intraperitoneal injection; once, for 38 days
Result:	Resulted in paralysis of both hind and forelimbs.

体内研究

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 200 μg (0.2 mL); i.p.; once, for 38 d) TFA has encephalitogenic activity in HLA-DR2 (DRB1*1501) mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	HLA-DR2 (DRB1*1501) mice
Dosage:	200 μg (0.2 mL)
Administration:	Intraperitoneal injection; once, for 38 days
Result:	Resulted in paralysis of both hind and forelimbs.

性状

Solid

溶解性数据

In Vitro:

H₂O : ≥ 50 mg/mL (18.55 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.3709 mL	1.8546 mL	3.7092 mL
5 mM	0.0742 mL	0.3709 mL	0.7418 mL
10 mM	0.0371 mL	0.1855 mL	0.3709 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶