Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate MOG (35-55 (acetate)),98.70%

产品编号:Bellancom-P1240B| 分子式:C120H181N35O31S| 分子量:2642.00

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货号 包装 价格 库存与货期 购买量 操作
Bellancom-P1240B
1500.00 杭州 北京(现货)
Bellancom-P1240B
4500.00 杭州 北京(现货)
Bellancom-P1240B
7600.00 杭州 北京(现货)

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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate MOG (35-55 (acetate))

产品介绍 Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate 是中枢神经鞘的一个次要成分。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 有致脑炎活性,诱导 T 细胞增殖。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 诱导 Th1 细胞因子反应以及相对高水平的 IgG 抗体产生。Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate 引发复发缓解性神经系统疾病,伴有广泛的斑块样脱髓鞘。
生物活性

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) acetate is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate produces a relapsing-remitting neurological disease with extensive plaque-like demyelination.

体外研究

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 0-50 μg/mL; 72 h; lymph nodes cells) acetate induces T cell proliferative and secretes Th1 cytokines including IFN-γ, TNF-α, IL-10, IL-4 and IL-5. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate increases the level of IgG.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 200 μg (0.2 mL); i.p.; once, for 38 d) acetate has encephalitogenic activity in HLA-DR2 (DRB1*1501) mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: HLA-DR2 (DRB1*1501) mice
Dosage: 200 μg (0.2 mL)
Administration: Intraperitoneal injection; once, for 38 days
Result: Resulted in paralysis of both hind and forelimbs.
体内研究

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55); 200 μg (0.2 mL); i.p.; once, for 38 d) acetate has encephalitogenic activity in HLA-DR2 (DRB1*1501) mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: HLA-DR2 (DRB1*1501) mice
Dosage: 200 μg (0.2 mL)
Administration: Intraperitoneal injection; once, for 38 days
Result: Resulted in paralysis of both hind and forelimbs.
性状Solid
溶解性数据
In Vitro: 

H2O : 100 mg/mL (37.85 mM; Need ultrasonic)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.3785 mL 1.8925 mL 3.7850 mL
5 mM 0.0757 mL 0.3785 mL 0.7570 mL
10 mM 0.0379 mL 0.1893 mL 0.3785 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)。-80°C 储存时,请在 6 个月内使用,-20°C 储存时,请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

参考文献

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