SSTR5 antagonist 2 hydrochloride|西域试剂

SSTR5 antagonist 2 hydrochloride,99.98%

产品编号：Bellancom-114191B| 分子式：C₃₂H₃₆ClFN₂O₅| 分子量：583.09

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货号	价格	库存与货期
Bellancom-114191B	￥4800.00	杭州北京（现货）
Bellancom-114191B	￥7500.00	杭州北京（现货）
Bellancom-114191B	￥15000.00	杭州北京（现货）

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SSTR5 antagonist 2 hydrochloride

产品介绍

SSTR5 antagonist 2 hydrochloride (compound 10) 是强效的、具有口服活性的生长激素抑制激素(受体)亚型 5 (SSTR5) 的选择性拮抗剂，有潜力用于 2 型糖尿病的研究。

生物活性

SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM).

体外研究

体内研究

SSTR5 antagonist 2 (compound 10) (10 mg/kg, orally) hydrochloride increases both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10 mg/kg.
SSTR5 antagonist 2 hydrochloride increases pancreatic insulin secretion as well as total and active GLP1 release, and demonstrates synergistic effects in combination with DPP4 inhibitors.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 33.33 mg/mL (57.16 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.7150 mL	8.5750 mL	17.1500 mL
5 mM	0.3430 mL	1.7150 mL	3.4300 mL
10 mM	0.1715 mL	0.8575 mL	1.7150 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

参考文献