(Rac)-BMS-816336
产品编号：Bellancom-101930A| 分子式：C21H27NO3| 分子量：341.44
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(Rac)-BMS-816336
| 产品介绍 | (Rac)-BMS-816336 (Compound 6n) 是 BMS-816336 的外消旋体。(Rac)-BMS-816336 是一种有效的人和小鼠 11β-羟类固醇脱氢酶 1 型 (11β-HSD1)抑制剂，其 IC50 分别为 10 nM 和 68 nM，并具有良好的代谢稳定性 。 | ||||||||||||
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| 生物活性 | (Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with IC50s of 10 nM and 68 nM, respectively. (Rac)-BMS-816336 has good metabolic stability. | ||||||||||||
| 体外研究 | |||||||||||||
| 体内研究 |
(Rac)-BMS-816336 (compound 6n) has good metabolic stability, and the remaining rates in human, mouse and rats of 88%,82% and 72%, respectively. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
| 体内研究 |
(Rac)-BMS-816336 (compound 6n) has good metabolic stability, and the remaining rates in human, mouse and rats of 88%,82% and 72%, respectively. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
| 性状 | Solid | ||||||||||||
| 溶解性数据 | |||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| 储存方式 |
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| 参考文献 |
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