Diprovocim-X
| 产品介绍 | Diprovocim-X (compound 35) 是一种有效的 TLR1/TLR2 (toll-like receptor 1/2) 激动剂，对 hTLR1/TLR2 和 mTLR1/TLR2 的 EC50 分别为 0.14 和 0.75 nM。Diprovocim-X 在小鼠体内是一种有效的佐剂，可刺激适应性免疫反应。 | ||||||||||||
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| 生物活性 | Diprovocim-X (compound 35) is a potent TLR1/TLR2 (toll-like receptor 1/2) agonist, with EC50 values of 0.14 and 0.75 nM for hTLR1/TLR2 and mTLR1/TLR2, respectively. Diprovocim-X is a potent adjuvant in vivo in mice, and serves to stimulate the adaptive immune response. | ||||||||||||
| 体外研究 |
Diprovocim-X stimulates release of TNF-α from (human) differentiated THP-1 cells proves dependent on both TLR2 and TLR1, but notably independent of TLR6. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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| 性状 | Solid | ||||||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| 参考文献 |
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