RNAIII-inhibiting peptide(TFA)|西域试剂

RNAIII-inhibiting peptide(TFA),99.75%

产品编号：Bellancom-P1452A| 分子式：C₄₇H₅₇F₃N₁₀O₁₃| 分子量：1027.01

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-P1452A		￥2100.00	杭州北京（现货）
Bellancom-P1452A		￥6300.00	杭州北京（现货）

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RNAIII-inhibiting peptide(TFA)

产品介绍

RNAIII-inhibiting peptide(TFA) 是一种有效的 Staphylococcus aureus 多肽抑制剂，在蜂窝组织炎、角膜炎、化脓性关节炎、骨肌炎和乳腺炎等疾病中有功效。

生物活性

RNAIII-inhibiting peptide(TFA) is a potent inhibitor of Staphylococcus aureus, effective in the diseases such as cellulitis, keratitis, septic arthritis, osteomylitis and mastitis.

体外研究

RNAIII-inhibiting peptide(TFA) is a potent inhibitor of Staphylococcus aureus. RNAIII-inhibiting peptide (RIP) inhibits the synthesis of both RNAII and RNAIII, while RAP activates in wild type S. aureus cells. RNAIII-inhibiting peptide (5 μg/10⁶ cells) potently reduces bacterial cell adhesion to HEp2 cells in the absence of serum, but with slight overall reduction the presence of serum. RNAIII-inhibiting peptide inhibits while RAP induces the phosphorylation of TRAP.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

RNAIII-inhibiting peptide (20 mg/kg, i.v.) decreases lethality in mice challenged with S. aureus ATCC 25923, with the lethality rate of 70%, and when combined with cefazolin, imipenem, vancomycin, the rates are 20%, 15% and 10%. RNAIII-inhibiting peptide (20 mg/kg, i.v.) also causes decreased lethality in mice challenged with S. aureus Smith, with the lethality rate of 75%, and the lethality rate decreases to 30%, 10% and 10% when combined with cefazolin, imipenem, vancomycin.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : ≥ 150 mg/mL (146.06 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.9737 mL	4.8685 mL	9.7370 mL
5 mM	0.1947 mL	0.9737 mL	1.9474 mL
10 mM	0.0974 mL	0.4869 mL	0.9737 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture