CMD178 TFA
| 产品介绍 | CMD178 TFA 是一种先导肽,能够持续地通过抑制 IL-2/s IL-2Rα 信号通路来减少 Foxp3 和 STAT5 的表达,并可抑制 Treg 细胞的发育。 | ||||||||||||||||
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| 生物活性 | CMD178 TFA is a lead peptide that consistently reduced the expression of Foxp3 and STAT5 induced by IL-2/s IL-2Rα signaling and inhibits Treg cell development. | ||||||||||||||||
| 体外研究 |
CMD178 TFA (100 μM) suppresses IL-2-induced STAT5 phosphorylation and inhibits Foxp3 expression in T cells. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
| 体内研究 | |||||||||||||||||
| 体内研究 | |||||||||||||||||
| 性状 | Solid | ||||||||||||||||
| 溶解性数据 |
In Vitro:
H2O : 2.5 mg/mL (2.59 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 | ||||||||||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| 储存方式 |
Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
| 参考文献 |

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