7-O-(Amino-PEG4)-paclitaxel
| 产品介绍 | 7-O-(Amino-PEG4)-paclitaxel 是一种 PEG 类、用于 ADC 的药物-接头偶联物，包含一个紫杉醇部分和一个氨基基团。氨基能够与羧酸、活化的 NHS 酯、羰基（酮、醛）等反应。7-O-(Amino-PEG4)-paclitaxel 可用于 ADC 的合成。 | |||||||||
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| 生物活性 | 7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC, containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-paclitaxel can be used in the synthesis of Antibody-Drug Conjugates (ADCs). | |||||||||
| 体外研究 |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | |||||||||
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| 性状 | Solid | |||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
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| 参考文献 |
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