2-甲基-3-羟基喹啉-4-羧酸 ,3-Hydroxy-2-methyl-4-quinolinecarboxylic acid ,97%

产品编号:SIGMA-183245| CAS NO:117-57-7| 分子式:C11H9NO3| 分子量:202.1867

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SIGMA-183245
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产品名称 2-甲基-3-羟基喹啉-4-羧酸
英文名称3-Hydroxy-2-methyl-4-quinolinecarboxylic acid
CAS编号117-57-7
产品熔点235 °C (dec.)(lit.)
产品沸点370.2±42.0 °C at 760 mmHg
产品密度1.4±0.1 g/cm3
产品闪点177.7±27.9 °C
精确质量203.058243
PSA70.42000
LogP3.35
外观性状黄色至绿色粉末
蒸气压0.0±0.9 mmHg at 25°C
折射率1.703
溶解性0.04 g/L (20 ºC)
稳定性

常温常压下稳定,避免与不相容材料,强氧化剂接触。

与强氧化剂反应。
储存条件

密封储存,储存于阴凉、干燥的库房。

相关文档

化学品安全说明书(MSDS)

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符号 GHS07
GHS07
信号词 Warning
危害声明 H315-H319-H335
警示性声明 P261-P305 + P351 + P338
个人防护装备 dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲) Xn: Harmful;
风险声明 (欧洲) R22;R36/37/38
安全声明 (欧洲) S26-S37/39-S36/37/39-S22
危险品运输编码 NONH for all modes of transport
WGK德国 1
海关编码 2933499090
Name: 3-Hydroxy-2-Methyl-4-Quinolinecarboxylic Acid 99% Material Safety Data Sheet
Synonym: None known
CAS: 117-57-7
Section 1 - Chemical Product MSDS Name:3-Hydroxy-2-Methyl-4-Quinolinecarboxylic Acid 99% Material Safety Data Sheet
Synonym:None known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
117-57-7 3-Hydroxy-2-Methyl-4-Quinolinecarboxyl 99 204-198-1
Hazard Symbols: XN
Risk Phrases: 22

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Harmful if swallowed.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion.
Extinguishing Media:
Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 117-57-7: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: yellow to green
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 220.00 - 223.00 deg C
Autoignition Temperature: 440 deg C ( 824.00 deg F)
Flash Point: 252 deg C ( 485.60 deg F)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature: >190 deg C
Solubility in water: 0.04 g/l (20 c)
Specific Gravity/Density:
Molecular Formula: C11H9NO3
Molecular Weight: 203.20

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 117-57-7 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
3-Hydroxy-2-Methyl-4-Quinolinecarboxylic Acid - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
Safety Phrases:
S 28A After contact with skin, wash immediately with
plenty of water.
S 37 Wear suitable gloves.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 117-57-7: 1
Canada
CAS# 117-57-7 is listed on Canada's NDSL List.
CAS# 117-57-7 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 117-57-7 is listed on the TSCA inventory.


SECTION 16 - ADDITIONAL INFORMATION
N/A

~88%

117-57-7结构式

117-57-7

文献:Yurovskaya, M. A.; Druzhinina, V. V.; Bundel', Yu. G. Chemistry of Heterocyclic Compounds (New York, NY, United States), 1982 , vol. 18, # 8 p. 871 - 872 Khimiya Geterotsiklicheskikh Soedinenii, 1982 , vol. 18, # 8 p. 1130

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文献:Journal of the American Chemical Society, , vol. 61, p. 2730,2732

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文献:DE615743 , ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 22, p. 482

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文献:Journal of Pharmacology and Experimental Therapeutics, , vol. 95, p. 185,186

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117-57-7

文献:Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, , vol. <5> 33 II, p. 92,93

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