4-(巯基甲基)苄腈 ,4-(4-cyanobenzyl)morpholin-4-ium
产品编号:SIGMA-OTV000427| CAS NO:37812-51-4| 分子式:C12H15N2O| 分子量:203.2598
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| 产品名称 | 4-(巯基甲基)苄腈 |
|---|---|
| 英文名称 | 4-(4-cyanobenzyl)morpholin-4-ium |
| CAS编号 | 37812-51-4 |
| 产品熔点 | 84ºC to 89ºC |
| 产品沸点 | 332.4±32.0 °C at 760 mmHg |
| 产品密度 | 1.1±0.1 g/cm3 |
| 产品闪点 | 154.8±25.1 °C |
| 精确质量 | 202.110611 |
| PSA | 36.26000 |
| LogP | 0.61 |
| 外观性状 | 白色至淡黄色结晶粉末 |
| 蒸气压 | 0.0±0.7 mmHg at 25°C |
| 折射率 | 1.573 |
| 稳定性 | 遵照规定使用和储存则不会分解。 |
| 储存条件 | 密闭于阴凉干燥环境中 |
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| 海关编码 | 2934999090 |
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Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 20/21/22 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Harmful by inhalation, in contact with skin and if swallowed. Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Harmful if absorbed through the skin. Causes skin burns. Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns. Inhalation: Harmful if inhaled. Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 37812-51-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 85.5 - 86 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H14N2O Molecular Weight: 202.26 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong reducing agents, acid chlorides. Hazardous Decomposition Products: Hydrogen cyanide, carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Not available. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 37812-51-4: XV1050000 LD50/LC50: Not available. Carcinogenicity: 4-(Morpholinomethyl)benzonitrile - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE SOLID, TOXIC, N.O.S.* Hazard Class: 8 (6.1) UN Number: 2923 Packing Group: III IMO Shipping Name: CORROSIVE SOLID, TOXIC, N.O.S. Hazard Class: 8 (6.1) UN Number: 2923 Packing Group: III RID/ADR Shipping Name: CORROSIVE SOLID, TOXIC, N.O.S. Hazard Class: 8 (6.1) UN Number: 2923 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. R 34 Causes burns. Safety Phrases: S 22 Do not breathe dust. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 37812-51-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 37812-51-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 37812-51-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
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| 文献:LIVERPOOL SCHOOL OF TROPICAL MEDICINE; O'NEILL, Paul; BIAGINI, Giancarlo; WARD, Stephen A.; BERRY, Neil Graham; NIXON, Gemma; AMEWU, Richard K.; PIDATHALA, Chandrakala; HONG, Weiqian David; GIBBONS, Peter; LEUNG, Suet Ching; PACOREL, Benedicte; SHARMA, Raman; LAWRENSON, Alexandre S.; SHONE, Alison E.; SRIVASTAVA, Abhishek; WARMAN, Ashley J. Patent: WO2012/69856 A1, 2012 ; Location in patent: Page/Page column 67 ; |
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| 文献:Chen, Wen-Xin; Zhang, Cai-Yun; Lu, Jian-Mei Journal of Chemical Research, 2013 , vol. 37, # 10 p. 611 - 614 |
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| 文献:ELI LILLY AND COMPANY Patent: WO2007/28083 A2, 2007 ; Location in patent: Page/Page column 91 ; WO 2007/028083 A2 |
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| 文献:Grochowski,E.; Boleslawska,T. Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1972 , vol. 20, p. 405 - 409 |
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