1-(4-Nitrophenylsulfonyl)piperidine ,1-(4-Nitrophenylsulfonyl)piperidine
产品编号:SIGMA-PH011403| CAS NO:64268-93-5| 分子式:C11H14N2O4S| 分子量:270.3049
VP-4509,一种抗甲氧西林耐药金黄色葡萄球菌(MRSA)试剂,MIC为49.3 µM.VP-4509对革兰氏阴性细菌铜绿假单胞菌也具有很高的抗菌活性。
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产品名称 | 1-(4-Nitrophenylsulfonyl)piperidine | ||||||||||||||||
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英文名称 | 1-(4-Nitrophenylsulfonyl)piperidine | ||||||||||||||||
CAS编号 | 64268-93-5 | ||||||||||||||||
产品描述 | VP-4509,一种抗甲氧西林耐药金黄色葡萄球菌(MRSA)试剂,MIC为49.3 µM.VP-4509对革兰氏阴性细菌铜绿假单胞菌也具有很高的抗菌活性。 | ||||||||||||||||
产品熔点 | 166ºC | ||||||||||||||||
产品沸点 | 435.9ºC at 760 mmHg | ||||||||||||||||
产品密度 | 1.374g/cm3 | ||||||||||||||||
产品闪点 | 217.4ºC | ||||||||||||||||
精确质量 | 270.06700 | ||||||||||||||||
PSA | 91.58000 | ||||||||||||||||
LogP | 3.31130 | ||||||||||||||||
折射率 | 1.592 | ||||||||||||||||
溶解性数据 | In Vitro:
DMSO : 25 mg/mL (92.49 mM; ultrasonic and warming and heat to 60°C) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
*以上所有助溶剂都可在西域网站选购。
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海关编码 | 2935009090 |
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Material Safety Data Sheet
Section1. Identification of the substance 1-[(4-Nitrophenyl)sulfonyl]piperidine Product Name: Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed.
H315:Causes skin irritation H319:Causes serious eye irritation H335:May cause respiratory irritation P261:Avoid breathing dust/fume/gas/mist/vapours/spray P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing P302+P352:IF ON SKIN: Wash with soap and water P321:Specific treatment (see on this label) P405:Store locked up Section3. Composition/information on ingredients. 1-[(4-Nitrophenyl)sulfonyl]piperidine Ingredient name: CAS number:64268-93-5 Section4. First aid measures Immediately wash skin with copious amounts of water for at least 15 minutes while removing Skin contact: contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Ingestion: Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Storage:Store in closed vessels. Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Not specified Appearance: Boiling point:No data Melting point:No data Flash point:No data Density:No data Molecular formula:C11H14N2O4S Molecular weight:270.3 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, sulfur oxides. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A |
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文献:US2006/84802 A1, ; Page/Page column 30 ; US 20060084802 A1 |
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文献:Palakurthy, Nani Babu; Dev, Dharm; Rana, Shubhasmin; Nadimpally, Krishna Chaitanya; Mandal, Bhubaneswar European Journal of Organic Chemistry, 2013 , # 13 p. 2627 - 2633 |
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文献:Mukaiyama, Teruaki; Kuroda, Kiichi; Aoki, Hidenori Chemistry Letters, 2005 , vol. 34, # 12 p. 1644 - 1645 |
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文献:Kweon, Deok-Heon; Kim, Ho-Kyun; Kim, Jeum-Jong; Chung, Hyun A.; Woo, Song Lee; Kim, Sung-Kyu; Yoon, Yong-Jin Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 1 p. 203 - 211 |
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文献:European Journal of Organic Chemistry, , # 13 p. 2627 - 2633 |
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文献:Chemistry Letters, , vol. 34, # 12 p. 1644 - 1645 |
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文献:Journal of Organic Chemistry, , vol. 69, # 9 p. 3166 - 3172 |
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文献:Bulletin of the Korean Chemical Society, , vol. 31, # 1 p. 234 - 237 |
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