N-Boc-5-溴吲哚 ,TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE ,97%

产品编号:SIGMA-557749| CAS NO:182344-70-3| 分子式:C13H14BrNO2| 分子量:296.1598

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货号 包装 价格 库存与货期 购买量 操作
SIGMA-557749
7252.00 杭州 北京(现货)
SIGMA-557749
1467.00 杭州 北京(现货)

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产品名称 N-Boc-5-溴吲哚
英文名称TERT-BUTYL 5-BROMOINDOLE-1-CARBOXYLATE
CAS编号182344-70-3
产品熔点56-57ºC(lit.)
产品沸点367.9ºC at 760mmHg
产品密度1.37g/cm3
产品闪点176.3ºC
精确质量295.02100
PSA31.23000
LogP4.18700
外观性状固体;White to Light yellow powder to crystal
蒸气压1.33E-05mmHg at 25°C
折射率1.576
稳定性

常温常压下稳定,避免与强氧化剂接触。

储存条件

密封储存,储存于阴凉、干燥的库房。

相关文档

化学品安全说明书(MSDS)

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符号 GHS07
GHS07
信号词 Warning
危害声明 H315-H319-H335
警示性声明 P261-P305 + P351 + P338
个人防护装备 dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲) Xi: Irritant;
风险声明 (欧洲) R36/37/38
安全声明 (欧洲) 26-36
危险品运输编码 NONH for all modes of transport
海关编码 2933990090
Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 1-BOC-5-bromoindole
Synonyms:tert-Butyl 5-bromo-1H-indole-1-carboxylate

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
P261:Avoid breathing dust/fume/gas/mist/vapours/spray
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:1-BOC-5-bromoindole
CAS number:182344-70-3

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels, refrigerated.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not specified
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula: C13H14BrNO2
Molecular weight: 296.2

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen bromide.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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文献:Takeda Pharmaceutical Company Limited Patent: EP1731505 A1, 2006 ; Location in patent: Page/Page column 29-30 ; EP 1731505 A1

~96%

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文献:THE TRUSTEES OF COLLUMBIA UNIVERSITY IN THE CITY OF NEW YORK Patent: WO2006/26368 A2, 2006 ; Location in patent: Page/Page column 91-92 ;

~53%

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文献:Hodgkinson, Roy C.; Schulz, Jurgen; Willis, Michael C. Organic and Biomolecular Chemistry, 2009 , vol. 7, # 3 p. 432 - 434

~70%

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文献:Shen, Xiaoqiang; Hyde, Alan M.; Buchwald, Stephen L. Journal of the American Chemical Society, 2010 , vol. 132, # 40 p. 14076 - 14078

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