美布罗芬宁 ,Mebrofenin
产品编号:SIGMA-1375706| CAS NO:78266-06-5| 分子式:C15H18BrN2O5| 分子量:386.2184
Mebrofenin (SQ 26962) 是亚氨基二乙酸 (IDA) 的一种。Mebrofenin 可用作 Tc-99m 的放射性标记试剂盒。Tc-99m Mebrofenin 是一种诊断剂,用于肝胆显像。Tc-99m Mebrofenin 是评价肝功能的首选放射性药物。
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产品名称 | 美布罗芬宁 | ||||||||||||||||
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英文名称 | Mebrofenin | ||||||||||||||||
CAS编号 | 78266-06-5 | ||||||||||||||||
产品描述 | Mebrofenin (SQ 26962) 是亚氨基二乙酸 (IDA) 的一种。Mebrofenin 可用作 Tc-99m 的放射性标记试剂盒。Tc-99m Mebrofenin 是一种诊断剂,用于肝胆显像。Tc-99m Mebrofenin 是评价肝功能的首选放射性药物。 | ||||||||||||||||
产品熔点 | 193-198ºC | ||||||||||||||||
产品沸点 | 577.4ºC at 760 mmHg | ||||||||||||||||
产品密度 | 1.5766 (rough estimate) | ||||||||||||||||
产品闪点 | 303ºC | ||||||||||||||||
精确质量 | 386.04800 | ||||||||||||||||
PSA | 106.94000 | ||||||||||||||||
LogP | 1.85700 | ||||||||||||||||
折射率 | 1.6520 (estimate) | ||||||||||||||||
溶解性 | Soluble in dimethylsulphoxide and ethanol. Insoluble in water. | ||||||||||||||||
溶解性数据 | In Vitro:
DMSO : 250 mg/mL (645.61 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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体外研究 | Tc-99mMebrofenin是一种99mTc标记的亚氨基二乙酸(IDA)衍生物,最初用于多种胆道疾病的诊断,最近用于肝功能评估。 | ||||||||||||||||
稳定性 | 远离氧化物。 | ||||||||||||||||
储存条件 | 存放在密封容器内,并放在阴凉,干燥处。储存的地方必须远离氧化剂。 |
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风险声明 (欧洲) | 36/37/38 |
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安全声明 (欧洲) | 24/25 |
危险品运输编码 | NONH for all modes of transport |
RTECS号 | MB9121850 |
海关编码 | 2924299090 |
Synonym:Mebrofenin Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 78266-06-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: light beige Odor: none reported pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 193.00 - 198.00 deg C Autoignition Temperature: Not applicable. Flash Point: 196 deg C ( 384.80 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: 196 deg C Solubility in water: soluble in methanol and ethanol Specific Gravity/Density: Molecular Formula: C15H19BrN2O5 Molecular Weight: 387.22 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, dust generation, excess heat, strong oxidants. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide, hydrogen bromide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 78266-06-5: MB9121850 LD50/LC50: Not available. Carcinogenicity: N-(3-Bromo-2,4,6-Trimethylphenylcarbamoylmethyl)Iminodiacetic Acid - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: Not regulated. Hazard Class: UN Number: Packing Group: IMO Shipping Name: Not regulated. Hazard Class: UN Number: Packing Group: RID/ADR Shipping Name: Not regulated. Hazard Class: UN Number: Packing group: Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 78266-06-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 78266-06-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 78266-06-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |