2-溴-2′-氯苯乙酮 ,2-Bromo-2'-chloroacetophenone ,95%
产品编号:SIGMA-594482| CAS NO:5000-66-8| 分子式:C8H6BrClO| 分子量:233.4896
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产品名称 | 2-溴-2′-氯苯乙酮 |
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英文名称 | 2-Bromo-2'-chloroacetophenone |
CAS编号 | 5000-66-8 |
产品熔点 | 162-166ºC (20 MMHG) |
产品沸点 | 248.9±15.0 °C at 760 mmHg |
产品密度 | 1.6±0.1 g/cm3 |
产品闪点 | 104.3±20.4 °C |
精确质量 | 231.929047 |
PSA | 17.07000 |
LogP | 2.62 |
外观性状 | 无色液体 |
蒸气压 | 0.0±0.5 mmHg at 25°C |
折射率 | 1.584 |
稳定性 | 常温常压下稳定,油状液体。沸点129-131℃(0.6kPa)。 |
储存条件 | 避光,阴凉干燥处,密封保存 |
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符号 |
![]() GHS05 |
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信号词 | Danger |
危害声明 | H314 |
警示性声明 | P280-P305 + P351 + P338-P310 |
个人防护装备 | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
危害码 (欧洲) | C:Corrosive; |
风险声明 (欧洲) | R34 |
安全声明 (欧洲) | S26-S36/37/39-S45 |
危险品运输编码 | UN 2922 8/PG 2 |
WGK德国 | 3 |
包装等级 | II |
危险类别 | 8 |
海关编码 | 2914700090 |
Synonym:2-Bromo-2'-chloroacetophenon Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Causes burns. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 5000-66-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: colorless - pale yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 162 - 166 deg C @ 20mmHg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H6BrClO Molecular Weight: 233.49 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, chlorine, carbon monoxide, carbon dioxide, hydrogen bromide, bromine. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 5000-66-8 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-Bromo-1-(2-chlorophenyl)ethan-1-one - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.* Hazard Class: 8 UN Number: 3265 Packing Group: III IMO Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3265 Packing Group: III RID/ADR Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. Hazard Class: 8 UN Number: 3265 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 5000-66-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 5000-66-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 5000-66-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
~81% ![]() 5000-66-8 |
文献:Denny, William Alexander; Hutchings, Richard H; Johnson, Douglas S; Kaltenbronn, James Stanely; Lee, Ho Huat; Leonard, Daniele Marie; Milbank, Jared Bruce John; Repine, Joseph Thomas; Rewcastle, Gordon William; White, Andrew David Patent: US2004/44057 A1, 2004 ; |
~83% ![]() 5000-66-8 |
文献:Chen, Zheng-Wang; Ye, Dong-Nai; Ye, Min; Zhou, Zhong-Gao; Li, Shen-Huan; Liu, Liang-Xian Tetrahedron Letters, 2014 , vol. 55, # 7 p. 1373 - 1375 |
~% ![]() 5000-66-8 |
文献:Kumar, Sunil; Gawandi, Vijay B.; Capito, Nicholas; Phillips, Robert S. Biochemistry, 2010 , vol. 49, # 36 p. 7913 - 7919 |
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文献:Lutz et al. Journal of Organic Chemistry, 1947 , vol. 12, p. 617,680 |
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