大鼠IgG,IgG From Rat Serum ,(≥95%, SDS-PAGE)

产品编号:Bellancom-R11309| CAS NO:Null| MDL NO:Null| 分子式:Null| 分子量:Null

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货号 包装 价格 库存与货期 购买量 操作
Bellancom-R11309
240.00 杭州 北京(现货)
Bellancom-R11309
1560.00 杭州 北京(现货)

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产品描述
IgG抗体可防止细菌,真菌和病毒引起的感染。母体IgG通过胎盘转移到胎儿,这对于新生儿抵抗感染的免疫防御至关重要,大鼠IgG通过分级分离和离子交换层析从合并的正常大鼠血清中纯化。IgG抗体亚型是免疫系统中最丰富的血清免疫球蛋白。它由B细胞分泌,存在于血液和细胞外液中。免疫球蛋白具有两条重链(H)和两条轻链(L),通过二硫键相连。每条轻链包含一个可变的N端区域和一个恒定的C端区域。重链具有一个可变的N端区域和三个或四个恒定的(CH1-CH4)C端区域。 IgG的四类可以是IgG1,IgG2,IgG3和IgG4。

General description
IgG antibody provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections[4] Rat IgG is purified from pooled normal rat serum by fractionation and ion-exchange chromatography.

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids, Immunoglobins have two heavy (H) and two light (L) chains, linked by disulphide linkages. Each light chain comprises one variable N-terminal region and a constant C-terminal region. Heavy chain has one variable N-terminal region and three or four constant (CH1-CH4) C-terminal region.[5] The four classes of IgG can be IgG1, IgG2, IgG3, and IgG4.[6]

Application
IgG from rat serum has been used:
•  in immunolabeling[8]
• in flow cytometry[9]
• in enzyme linked immunosorbent assay[10]
• as a control in neutrophil depletion assay
使用大鼠血清中的IgG作为:
•免疫标记
•流式细胞仪
•在酶联免疫吸附测定中
•作为中性粒细胞耗竭试验的对照
IgG抗体具有巨大的治疗潜力,其片段可结晶(Fc)区有助于治疗性抗体的发展。

包装
10, 100 mg in poly bottle

Biochem/physiol Actions
IgG antibody have enormous therapeutic potential and its fragment crystallizable (Fc) region contributes for the development of therapeutic antibody.[7]

Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

性质
Quality Level 200
grade reagent grade
assay ≥95% (SDS-PAGE)
form essentially salt-free, lyophilized powder
conjugate unconjugated
storage temp. 2-8°C

安全信息
个人防护装备 Eyeshields, Gloves, type N95 (US)
RIDADR NONH for all modes of transport
WGK德国 WGK 3

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