醋酸曲安西龙双,标准溶液,溶剂:甲醇, 1000μg/mL

产品编号:西域质检-TM21141| CAS NO:67-78-7| 分子式:C25H31FO8| 分子量:478.507

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货号 包装 价格 库存与货期 购买量 操作
西域质检-TM21141
1500.00 杭州 北京(现货)

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醋酸曲安西龙双

本标准物质主要用于测量仪器校准,分析方法评价和质量控制,以及食品,卫生,环境和农业等领域相应成分含量测定与残留检测,也可用于量值溯源或作为标准储备溶液,通过逐级稀释配制成各种工作用标准溶液等。

一、样品制备

本标准物质采用纯度准确定值的醋酸曲安西龙双纯品为原料,以HPLC级甲醇为溶剂,采用重量-容量法准确配制而成。
 醋酸曲安西龙双,英文名称: Triamcinolone Diacetate,CAS No. : 67-78-7

二、溯源性及定值方法

本标准物质以配制值作为标准值,采用高效液相色谱-二极管阵列检测器(HPLC-DAD)对本批次标准物质和质量控制对照样品进行比对,核验配制值。通过使用满足计量学特性要求的制备方法,测量方法和计量器具,保证标准物质的量值溯源性。

三、特性量值及不确定度

标准值:1000μg/mL,相对扩展不确定度(k=2):2%
 标准值的不确定度综合考虑了原料纯度定值结果,制备过程,量值核验以及均匀性,稳定性等引入的不确定度分量。

四、均匀性检验及稳定性考察

依据JJF1343-2012[标准物质定值的通用原则及统计学原理],对分装后的样品进行随机抽样,对溶液浓度进行均匀性检验,稳定性考察。结果表明,本标准物质均匀性,稳定性良好。
 本标准物质量值自定值日期起,有效期12个月, 研制单位将继续跟踪监测该标准物质的稳定性,有效期内如发现量值变化,将及时通知用户。

五、包装、运输和贮存、使用及注意事项

1.包装:本标准物质采用硼硅酸盐玻璃安瓿瓶包装,约1mL/支,移取或稀释时请以移液管量取为准。
 2.贮存:运输时应避免挤压,碰撞;冷藏(2~8)℃,置于阴凉处贮存。
 3.使用:启封前于室温(20±3)℃平衡,并充分摇匀。安瓿瓶一经打开,应立即使用,不可再次熔封后作为标准物质使用。

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风险声明 (欧洲) R10:Flammable.
安全声明 (欧洲) S26-S36/37/39-S45
危险品运输编码 UN 3272 3/PG 3
WGK德国 3
包装等级 III
危险类别 3
海关编码 29349990

Section 1. Chemical Product and Company Identification
Triamcinolone diacetate
Common Name/
Trade Name
Triamcinolone diacetate

Section 4. First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at
least 15 minutes. Get medical attention if irritation occurs.
Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Serious Skin ContactNot available.
InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get
medical attention.
Serious InhalationNot available.
IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an
unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight
clothing such as a collar, tie, belt or waistband.
Serious IngestionNot available.

Section 5. Fire and Explosion Data
Flammability of the Product May be combustible at high temperature.
Auto-Ignition Temperature Not available.
Flash PointsNot available.
Flammable LimitsNot available.
Products of CombustionThese products are carbon oxides (CO, CO2), halogenated compounds.
Fire Hazards in Presence of Slightly flammable to flammable in presence of heat.
Various Substances
Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
Risks of explosion of the product in presence of static discharge: Not available.
of Various Substances
SMALL FIRE: Use DRY chemical powder.
Fire Fighting Media
and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet.
As with most organic solids, fire is possible at elevated temperatures.
Special Remarks on
When heated to decomposition it emits acrid smoke and toxic fumes of Fluorine.
Fire Hazards
Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust
Hazardsexplosion hazard.

Section 6. Accidental Release Measures
Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by
spreading water on the contaminated surface and dispose of according to local and regional authority
requirements.
Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water
on the contaminated surface and allow to evacuate through the sanitary system.
Triamcinolone diacetate

Section 7. Handling and Storage
PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not
breathe dust.
StorageKeep container tightly closed. Keep container in a cool, well-ventilated area.

Section 8. Exposure Controls/Personal Protection
Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below
recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
airborne contaminants below the exposure limit.
Personal Protection
Safety glasses. Lab coat. Dust respirator. Use a dust respirator if ventilation is inadequate and is handling of
material creates visible dust clouds. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used
a Large Spillto avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this product.
Exposure LimitsNot available.

Section 9. Physical and Chemical Properties
Physical state and appearance Solid. (Powdered solid. Crystalline powder.)OdorSlight.
TasteNot available.
Molecular Weight478.51 g/mole
ColorWhite. Off-white.
pH (1% soln/water)Not applicable.
Boiling PointNot available.
Melting Point186°C (366.8°F) - 188 C.
Critical TemperatureNot available.
Not available.
Specific Gravity
Vapor PressureNot applicable.
Vapor DensityNot available.
VolatilityNot available.
Odor ThresholdNot available.
Not available.
Water/Oil Dist. Coeff.
Ionicity (in Water)Not available.
Not available.
Dispersion Properties
SolubilityInsoluble in cold water, hot water.

Section 10. Stability and Reactivity Data
StabilityThe product is stable.
Not available.
Instability Temperature
Conditions of InstabilityExcess heat
Incompatibility with variousNot available.
substances
CorrosivityNon-corrosive in presence of glass.
Triamcinolone diacetate
Special Remarks onNot available.
Reactivity
Special Remarks onNot available.
Corrosivity
PolymerizationWill not occur.

Section 11. Toxicological Information
Routes of EntryInhalation. Ingestion.
Toxicity to AnimalsLD50: Not available.
LC50: Not available.
Chronic Effects on Humans Not available.
Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation.
Humans
Special Remarks onNot available.
Toxicity to Animals
Special Remarks on
May cause adverse reproductive effects and birth defects (teratogenic) based on animal test data
Chronic Effects on Humans
Special Remarks on otherAcute Potential Health Effects:
Toxic Effects on HumansSkin: May cause skin irritation with itching, erythema, folliculitis, pustules, pyoderma, vesiculation, hyperesthesia.
Eyes: Dust may cause eye irritation.
Inhalation: Dust may cause respiratory tract irritation.
Ingestion: May cause gastrointestinal tract irritation with indigestion. Ingestion as well as if orally-inhaled may
cause adverse effects which may include decreased or blurred vision, frequent urination, increased thirst, loss or
increase of appetite, nervousness or restlessness, and trouble sleeping, hypertension, electrolyte imbalances due
to sodiuim/fluid retention, hyperglycemia and glycosuria.
Note: Possible allergic reaction to material if inhaled, ingested or in contact with skin.
Chronic Potential Health Effects: Possible hypersensitization, acne or other skin problems, hip or shoulder pain,
fullness in face, swelling of feet or lower legs, menstrual irregularities, hirsutism, hypopigmentation, nausea,
vomiting, irregular heartbeat, muscle cramps, weakness, osteoporisis, increased susceptibilitiy to infection,
psychosis, and eye problems (cataracts, glaucoma with possible damage to the optic nerve).
Prolonged or repeated skin contact may cause itching, allergic contact dermatitis.
Medical Conditons Aggravated by Exposure: Hypersensitivity to this material or other corticosteroids; ocular
herpes simples; active alcoholism; AIDS or HIV infection; heart disease or hypertension; diabetes mellitus;
myasthenia gravis; impaired liver or kidney function; esophagitis; gastritis or peptic ulcer; chickenpox or measles
(including recent exposure); tuberculosis; and system fungal infections.

Section 12. Ecological Information
Not available.
Ecotoxicity
BOD5 and CODNot available.
Products of BiodegradationPossibly hazardous short term degradation products are not likely. However, long term degradation products may
arise.
Toxicity of the ProductsThe products of degradation are more toxic than the product itself.
of Biodegradation
Special Remarks on theNot available.
Products of Biodegradation
Triamcinolone diacetate

Section 13. Disposal Considerations
Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental
control regulations.

Section 14. Transport Information
DOT ClassificationNot a DOT controlled material (United States).
Not applicable.
Identification
Not applicable.
Special Provisions for
Transport
DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
No products were found.
Federal and State
Regulations
CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has found
to cause cancer which would require a warning under the statute: No products were found.
Proposition 65
Warnings
California prop. 65: This product contains the following ingredients for which the State of California has found
to cause birth defects which would require a warning under the statute: No products were found.
Other RegulationsEINECS: This product is on the European Inventory of Existing Commercial Chemical Substances.
Other ClassificationsWHMIS (Canada) Not controlled under WHMIS (Canada).
DSCL (EEC)This product is not classified according Not applicable.
to the EU regulations.
Health Hazard
HMIS (U.S.A.)1 National Fire Protection
1 Flammability
1 Association (U.S.A.)
Fire Hazard
1 0 Reactivity
Health
Reactivity
0
Specific hazard
Personal Protection
E
WHMIS (Canada)
(Pictograms)
DSCL (Europe)
(Pictograms)
TDG (Canada)
(Pictograms)
Triamcinolone diacetate
ADR (Europe)
(Pictograms)
Protective Equipment
Gloves.
Lab coat.
Dust respirator. Be sure to use an
approved/certified respirator or
equivalent.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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