红景天苷|cas:10338-51-9|西域试剂

红景天苷,分析标准品,HPLC≥99.2%

产品编号：西域质检-TM23964| CAS NO：10338-51-9| 分子式：C₁₄H₂₀O₇| 分子量：300.304

Salidroside 是一种脯氨酰内肽酶 (prolyl endopeptidase) 抑制剂。Salidroside 可通过激活 mTOR 信号缓解肿瘤恶病质小鼠模型中的恶病质症状。Salidroside 还能通过增强 PINK1/Parkin 介导的线粒体自噬来保护多巴胺能神经元。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
西域质检-TM23964		￥190.00	杭州北京（现货）
西域质检-TM23964		￥650.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

红景天苷

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Salidroside(红景天苷)

Product Code(产品编号) 710096-100mg

Lot Number(产品批号) 23031080

CAS No. 10338-51-9

Mol. Weight(分子量) 300.30

Mol. Formula(分子式) C₁₄H₂₀O₇

Melting Point(熔点) N/A

Expiry Date(失效日期) 2029-Mar-29

Boiling point(沸点) N/A

Appearance(外观) White to Off-White Solid
(白色固体)______

Storage Temp(存储条件) (-18±5)℃,Keep in the shade
冷冻(-18±5)℃,置于阴凉处

C E R T I F I E D

Purity

99.7%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
2023-Mar-30		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

符号	GHS07
信号词	Warning
危害声明	H319
警示性声明	P305 + P351 + P338
危害码 (欧洲)	Xi
风险声明 (欧洲)	36
安全声明 (欧洲)	26
危险品运输编码	NONH for all modes of transport
RTECS号	LZ5901900
海关编码	2932999099

1. 物质的识别

产品名：	Salidroside
CAS号：	10338-51-9
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Salidroside
别名：	Rhodioloside
分子式：	C14H20O7
分子量：	300.3

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	2-8°C, protect from light

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

上游产品 7
40661-45-8 67-56-1 28251-63-0 50-99-7
501-94-0 2492-87-7 133-99-3
下游产品 1
492-62-6

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56. [IF=2.942] Zhang Dan et al."Salidroside mitigates skeletal muscle atrophy in rats with cigarette smoke-induced COPD by up-regulating myogenin and down-regulating myostatin expression."Bioscience Rep. 2019 Nov;39(11):BSR20190440

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51. [IF=4.679] Yuan Yuan et al."Salidroside ameliorates liver metabonomics in relation to modified gut-liver FXR signaling in furan-induced mice."Food Chem Toxicol. 2020 Jun;140:111311

50. [IF=5.076] Zhang Zepeng et al."Shen-Hong-Tong-Luo Formula Attenuates Macrophage Inflammation and Lipid Accumulation through the Activation of the PPAR-γ/LXR-α/ABCA1 Pathway."Oxid Med Cell Longev. 2020;2020:3426925

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48. [IF=1.297] Shi Kai et al."Salidroside protects retinal endothelial cells against hydrogen peroxide-induced injury via modulating oxidative status and apoptosis."Biosci Biotech Bioch. 2015 Sep;79(9):1406-1413

47. [IF=1.851] Xujiao Huang et al."Salidroside protects PC12 cells from Aβ1‑40‑induced cytotoxicity by regulating the nicotinamide phosphoribosyltransferase signaling pathway."Mol Med Rep. 2017 Sep;16(3):2700-2706

46. [IF=2.1] Lin Sun et al."Salidroside slows the progression of EA.hy926 cell senescence by regulating the cell cycle in an atherosclerosis model."Mol Med Rep. 2018 Jan;17(1):257-263

45. [IF=2.371] Wang Xu-Lei et al."Salidroside Improves Doxorubicin-induced Cardiac Dysfunction by Suppression of Excessive Oxidative Stress and Cardiomyocyte Apoptosis."J Cardiovasc Pharm. 2013 Dec;62(6):512-523

44. [IF=2.629] Zhang Bu-Chun et al."Salidroside Decreases Atherosclerotic Plaque Formation in Low-Density Lipoprotein Receptor-Deficient Mice."Evid-Based Compl Alt. 2012;2012:607508

43. [IF=3.046] Liwei Dong et al."Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1."Oncotargets Ther. 2015; 8: 3649–3664

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38. [IF=6.06] Jiahong Han et al."Compatibility effects of ginseng and Ligustrum lucidum Ait herb pair on hematopoietic recovery in mice with cyclophosphamide-induced myelosuppression and its material basis."J Ginseng Res. 2020 Mar;44:291

37. Nan, Xingmei, et al. "Bioactive fraction of Rhodiola algida against chronic hypoxia-induced pulmonary arterial hypertension and its anti-proliferation mechanism in rats." Journal of ethnopharmacology 216 (2018): 175-183.https://doi.org/10.1016/j.jep.2018.0

36. Hu, Fangli, Xiaoyan Liao, and Zilin Chen. "Determination of three phenylethanoid glycosides in Osmanthus fragrans fruits by high‐performance liquid chromatography with fluorescence detection." Journal of separation science 41.21 (2018): 3995-4000. https://

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27. 黄菲菲,李耀浙,张婷,王良兴,黄晓颖.红景天苷通过抑制氧化应激防治大鼠低氧性肺动脉高压[J].中国病理生理杂志,2018,34(03):500-506.

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25. 刘莲, 崔书彦, 王晨雪, et al. 红景天苷联合阿霉素对裸鼠HepG2肝癌的影响研究[J]. 现代中西医结合杂志, 2019(21).

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13. 马莹,刘晶,潘涛.红景天苷对H9c2心肌细胞应激高糖损伤的保护作用及机制研究[J].南京中医药大学学报,2019,35(04):442-447.

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11. 黄媛恒,谢剑,黄创明,韦仙琴,林心媚,刘芳铭,李映新.红景天苷体外灌流对大鼠心肌细胞膜钠通道电流的影响[J].山东医药,2016,56(07):31-33.

10. 陈红红, 莫书荣, 吴忧. 红景天苷与黄芪注射液协同对人肝癌HepG2细胞增殖的抑制作用[J]. 基因组学与应用生物学, 2016, 35(009):2241-2245.

9. 秦雪琴,陈悦,雷尚芳,陈德森.红景天甙防治兔肝移植术后疲劳综合征的实验研究[J].海南医学,2017,28(12):1893-1896.

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6. 徐锋, 杨烨, 舒秋娥,等. 大血藤药材的UPLC指纹图谱分析[J]. 中国实验方剂学杂志, 2013.

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