天然产物/西红花苷Ⅱ|cas:55750-84-0|西域试剂

天然产物/西红花苷Ⅱ,≥98%

产品编号：西域质检-TM40783| CAS NO：55750-84-0| 分子式：C₃₈H₅₄O₁₉| 分子量：814.824

Crocin II 是从栀子 (Gardenia jasminoides) 果实中分离出来的，具有抗氧化，抗癌和抗抑郁活性。Crocin II 抑制NO产生，IC50 值为 31.1 μM。Crocin II 抑制 iNOS 和 COX-2 的蛋白质和 m-RNA 的表达。

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货号	包装	价格	库存与货期	购买量	操作
西域质检-TM40783		￥757.00	杭州北京（现货）

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天然产物/西红花苷Ⅱ

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Crocin II

Product Code(产品编号) 724581-20mg

Lot Number(产品批号) -

CAS No. 55750-84-0

Mol. Weight(分子量) 814.82

Mol. Formula(分子式) C₃₈H₅₄O₁₉

Melting Point(熔点) N/A

Expiry Date(失效日期) -

Boiling point(沸点) N/A

Appearance(外观) Dark Red Solid

Storage Temp(存储条件) (2~8)℃,dark

C E R T I F I E D

Purity

98.1%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
-		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

海关编码	29389090

1. 物质的识别

产品名：	Crocin-II
CAS号：	55750-84-0
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Crocin-II
分子式：	C38H54O19
分子量：	814.82

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	2-8°C, dry, sealed

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

14. [IF=2.343] Ye Xiao et al."Comprehensive profiling of phytochemicals in the fruits of Gardenia jasminoides Ellis and its variety using liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry."Journal of Natural Medicines.

13. [IF=7.514] Hao Huang et al."Integrated natural deep eutectic solvent and pulse-ultrasonication for efficient extraction of crocins from gardenia fruits (Gardenia jasminoides Ellis) and its bioactivities."Food Chem. 2022 Jun;380:132216

12. [IF=3.935] Jie Li et al."Quality consistency evaluation between dispensing granules and traditional decoction of Gardeniae Fructus based on chemical similarity and bioequivalence."J Pharmaceut Biomed. 2022 May;213:114708

11. [IF=2.447] Jianrong Chen et al."Anti‑inflammatory activities of Gardenia jasminoides extracts in retinal pigment epithelial cells and zebrafish embryos."Exp Ther Med. 2021 Jul;22(1):1-9

10. [IF=4.411] Chunnan Li et al."Screening of the Hepatotoxic Components in Fructus Gardeniae and Their Effects on Rat Liver BRL-3A Cells."Molecules. 2019 Jan;24(21):3920

9. [IF=2.896] Lu Wang et al."Rapid assay for testing superoxide anion radical scavenging activities to natural pigments by ultra-high performance liquid chromatography-diode-array detection method."Anal Methods-Uk. 2015 Feb;7(4):1535-1542

8. 朱颖洁,杨亚洁,李群和,邹盈,罗自生.栀子果油的生物活性成分及抗氧化活性评价[J].现代食品科技,2021,37(02):103-113+102.

7. 曹虹虹, 严维花, 郭爽,等. 栀子姜炙工艺及姜炙前后化学成分变化研究[J]. 中国中药杂志, 2019(24).

6. 曹虹虹, 严维花, 郭爽,等. 基于多成分测定及指纹图谱评价不同产地栀子质量[J]. 中国中药杂志, 2019, v.44(18):196-203.

5. 田瑞华, 彭平, 刘希,等. 栀子药材的质量表征与产地的关联性研究[J]. 世界科学技术:中医药现代化, 2019(5):882-891.

4. 彭平, 张蓓, 杜菁,等. 基于天然麝香-牛黄和4个植物药味的安宫牛黄丸特征图谱质量表征研究[J]. 中草药, 2019(14).

3. 谢典, 王萌萌, 徐步斌,等. 江西产西红花中西红花苷-I和苷-II的静态分析[J]. 江西科技师范大学学报, 2019, No.190(06):69-71.

2. 王萌萌徐步斌周斌等. HPLC法测定西红花不同部位中西红花苷-Ⅰ和苷-Ⅱ[J]. 中成药 2019 041(005):1102-1105.

1. 戴智慧黄士文倪穗等. HPLC法测定浙江慈溪水稻田栽培的西红花中西红花苷Ⅰ、Ⅱ含量的研究[J]. 中国野生植物资源 2016 35(002):14-18.