天然产物/羟基红花黄色素A|cas:78281-02-4|西域试剂

天然产物/羟基红花黄色素A,≥98%

产品编号：西域质检-TM41667| CAS NO：78281-02-4| 分子式：C₂₇H₃₂O₁₆| 分子量：612.533

羟基红花黄色素A (Hydroxysafflor yellow A)是从中药红花中分离出的黄酮类天然产物，具有抗癌活性。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
西域质检-TM41667		￥345.00	杭州北京（现货）

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天然产物/羟基红花黄色素A

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Hydroxysafflor Yellow A

Product Code(产品编号) 726783-20mg

Lot Number(产品批号) -

CAS No. 78281-02-4

Mol. Weight(分子量) 612.54

Mol. Formula(分子式) C₂₇H₃₂O₁₆

Melting Point(熔点) N/A

Expiry Date(失效日期) -

Boiling point(沸点) N/A

Appearance(外观) Yellow Solid_____________

Storage Temp(存储条件) (-18±5)℃,Keep in the shade

C E R T I F I E D

Purity

99.8%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
-		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

安全声明 (欧洲)	24/25

1. 物质的识别

产品名：	hydroxysafflor-yellow-A
CAS号：	78281-02-4
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	hydroxysafflor-yellow-A
别名：	Safflomin A; HSYA
分子式：	C27H32O16
分子量：	612.53

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	2-8°C, protect from light

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

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58. [IF=4.225] Shang Ting et al."Xuebijing Injection Maintains GRP78 Expression to Prevent Candida albicans–Induced Epithelial Death in the Kidney."Front Pharmacol. 2020 Jan;0:1416

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54. [IF=5.81] Fangma Yijia et al."Hydroxysafflor Yellow A and Anhydrosafflor Yellow B Protect Against Cerebral Ischemia/Reperfusion Injury by Attenuating Oxidative Stress and Apoptosis via the Silent Information Regulator 1 Signaling Pathway."Front Pharmacol. 2021 Sep

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52. [IF=7.514] Xin Tong et al."Greener extraction process and enhanced in vivo bioavailability of bioactive components from Carthamus tinctorius L. by natural deep eutectic solvents."Food Chem. 2021 Jun;348:129090

51. [IF=7.514] Liuwei Zhao et al."Safflomin A: A novel chemical marker for Carthamus tinctorius L. (Safflower) monofloral honey."Food Chem. 2022 Jan;366:130584

50. [IF=2.1] Bin Ni et al."Hydroxysafflor yellow A protects against angiotensin II‑induced hypertrophy."Mol Med Rep. 2018 Oct;18(4):3649-3656

49. [IF=2.173] Wenlu Li et al."Hydroxysafflor yellow A protects methylglyoxal-induced injury in the cultured human brain microvascular endothelial cells."Neurosci Lett. 2013 Aug;549:146

48. [IF=2.233] Zhenzhen Ni et al."Inhibitory effects of hydroxysafflor yellow A on the formation of advanced glycation endproducts in vitro."Biological & Pharmaceutical Bulletin. 2012 Aug 31

47. [IF=2.547] Jing Zhou et al."Pharmacokinetic Study on Protocatechuic Aldehyde and Hydroxysafflor Yellow A of Danhong Injection in Rats with Hyperlipidemia."Pharmacology. 2018;102(3-4):154-160

46. [IF=2.896] Lu Wang et al."Rapid assay for testing superoxide anion radical scavenging activities to natural pigments by ultra-high performance liquid chromatography-diode-array detection method."Anal Methods-Uk. 2015 Feb;7(4):1535-1542

45. [IF=3.046] Liwei Dong et al."Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1."Oncotargets Ther. 2015; 8: 3649–3664

44. [IF=3.845] Zhang Xianhua et al."Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds."Front Pharmacol. 2017 Jul;0:452

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39. Yu, Lu, et al. "Hydroxysafflor yellow a confers neuroprotection from focal cerebral ischemia by modulating the crosstalk between JAK2/STAT3 and SOCS3 signaling pathways." Cellular and molecular neurobiology (2020): 1-11.

38. Zhou, Donglai, et al. "Hydroxysafflor Yellow A mitigated myocardial ischemia/reperfusion injury by inhibiting the activation of the JAK2/STAT1 pathway." International journal of molecular medicine 44.2 (2019): 405-416.https://doi.org/10.3892/ijmm.2019.4230

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