天然产物/马钱苷酸|cas:22255-40-9|西域试剂

天然产物/马钱苷酸,≥98%

产品编号：西域质检-TM44518| CAS NO：22255-40-9| 分子式：C₁₆H₂₄O₁₀| 分子量：376.356

Loganic acid 是从山茱萸果实中分离得到的一种环烯醚萜。Loganic acid 能调节饮食引起的动脉粥样硬化和氧化还原状态。Loganic acid 具有很强的自由基清除活性，对重金属介导的毒性有显著的细胞保护作用。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
西域质检-TM44518		￥345.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

天然产物/马钱苷酸

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Loganic Acid(马钱苷酸)

Product Code(产品编号) 723829-20mg

Lot Number(产品批号) -

CAS No. 22255-40-9

Mol. Weight(分子量) 376.36

Mol. Formula(分子式) C₁₆H₂₄O₁₀

Melting Point(熔点) N/A

Expiry Date(失效日期) -

Boiling point(沸点) N/A

Appearance(外观) White to Off-White Solid
(白色固体)______

Storage Temp(存储条件) (-18±5)℃,Keep in the shade
冷冻(-18±5)℃,置于阴凉处

C E R T I F I E D

Purity

99.4%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
-		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

危险品运输编码	NONH for all modes of transport

1. 物质的识别

产品名：	Loganic-acid
CAS号：	22255-40-9
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Loganic-acid
分子式：	C16H24O10
分子量：	376.36

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	4°C, protect from light, dry, sealed

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

20. [1.698] Mengjie Xue et al."Illumination on Chemical Compounds from Qufeng Zhitong Capsule and Its Potential Pharmacological Mechanism against Rheumatoid Arthritis Based on UHPLC/Q-Orbitrap-MS Combined with Network Pharmacology Analysis."International Journal of A

19. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

18. [IF=2.594] Xue Mengjie et al."Quantitative Analysis of Multicomponents in Qufeng Zhitong Capsule and Application of Network Pharmacology to Explore the Anti-Inflammatory Activity of Focused Compounds."Journal of Analytical Methods in Chemistry.2022;2022:4229945

17. [IF=5.195] Zehua Jin et al."Network pharmacology study to reveal active compounds of Qinggan Yin formula against pulmonary inflammation by inhibiting MAPK activation."JOURNAL OF ETHNOPHARMACOLOGY.2022 Oct;296:115513

16. [IF=1.902] Huan Liu et al."A new and effective evaluation method for Radix Gentianae Macrophyllae herbs based on 2-phenylethyl β-d-glucopyranoside, 2-methoxyanofinic acid and gentioxepine by UPLC–QTOF–MS exploring and HPLC–DAD quantification."Biomed Chromatogr. 2021

15. [IF=3] Hui-Qin PAN et al."Plant metabolomics for studying the effect of two insecticides on comprehensive constituents of Lonicerae Japonicae Flos."Chin J Nat Medicines. 2021 Jan;19:70

14. [IF=3.935] Hengqiang Zhao et al."An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicerae Japonicae."J Pharmaceut Biomed. 2019 Oct;175:112758

13. [IF=4.142] Wang Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4

12. [IF=4.759] Wenhua Ji et al."Water-compatible micron-sized monodisperse molecularly imprinted beads for selective extraction of five iridoid glycosides from Cornus officinalis fructus."J Chromatogr A. 2017 Jun;1504:1

11. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang, An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera

10. Hengqiang Zhao, Changjiangsheng Lai, Minmin Zhang, Siduo Zhou, Qian Liu, Daijie Wang, Yanling Geng, Xiao Wang, An improved 2D-HPLC-UF-ESI-TOF/MS approach for enrichment and comprehensive characterization of minor neuraminidase inhibitors from Flos Lonicera

9. Tao, Yi, et al. "Integrating UHPLC–MS/MS quantification and DAS analysis to investigate the effects of wine-processing on the tissue distributions of bioactive constituents of herbs in rats: Exemplarily shown for Dipsacus asper." Journal of Chromatography

8. 吴昕怡,刘秀嶶,屈云慧,石萍萍,杨雁,李智敏,田浩,谷丽萍.Box-Behnken设计-响应面法优化滇龙胆药材产地初加工工艺[J].中国药房,2020,31(15):1830-1835.

7. 朱姮, 于金倩, 刘倩,等. 基于RRLC-DAD-ESI-Q-TOF-MS技术的山东金银花多指标定量指纹图谱分析[J]. 中国实验方剂学杂志, 2017, 023(019):82-89.

6. 马云, 王尧尧, 王蕾,等. 忍冬花发育期间形态与13种活性成分含量变化[J]. 中药材, 2018, 041(007):1559-1565.

5. 张敏敏, 刘代成, 王岱杰,等. SPME-GC/MS联合HSDE-HPLC-DAD分析表征金银花新品种中的主要化学成分[J]. 天然产物研究与开发, 2016, 028(009):1390-1396,1413.

4. 吴昕怡刘秀嶶屈云慧等. Box-Behnken设计-响应面法优化滇龙胆药材产地初加工工艺[J]. 中国药房 2020年31卷15期 1830-1835页 ISTIC PKU CA 2020.

3. 张瑜, 杨健, 秦振娴,等. 大孔吸附树脂富集金银花中环烯醚萜苷类成分的工艺优选[J]. 中国实验方剂学杂志, 2016(24):18-21.

2. 张瑜杨健秦振娴等. UPLC测定不同产地金银花中环烯醚萜苷类成分含量[J]. 中药材 2016 39(009):2053-2055.

1. 刘倩张敏敏李圣波等. HPLC-DAD法测定西藏产区金银花花蕾及叶中化学成分含量[J]. 山东科学 2018 031(004):20-25.