丹酚酸A|cas:96574-01-5|西域试剂

丹酚酸A,分析标准品,HPLC≥99%

产品编号：西域质检-TM45283| CAS NO：96574-01-5| 分子式：C₂₆H₂₂O₁₀| 分子量：494.447

Salvianolic acid A 可通过抑制基质金属钛酶 9 (MMP-9) 和抗炎作用来保护血脑屏障。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
西域质检-TM45283		￥750.00	杭州北京（现货）
西域质检-TM45283		￥1500.00	杭州北京（现货）

增值税发票√顺丰快递√订货电话：18601927057

丹酚酸A

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Salvianolic Acid A

Product Code(产品编号) 725343-100mg

Lot Number(产品批号) -

CAS No. 96574-01-5

Mol. Weight(分子量) 494.45

Mol. Formula(分子式) C₂₆H₂₂O₁₀

Melting Point(熔点) N/A

Expiry Date(失效日期) -

Boiling point(沸点) N/A

Appearance(外观) Yellow Solid__________

Storage Temp(存储条件) (2~8)℃,Keep in the shade

C E R T I F I E D

Purity

99%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
-		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

安全声明 (欧洲)	24/25
危险品运输编码	NONH for all modes of transport

1. 物质的识别

产品名：	Salvianolic-acid-A
CAS号：	96574-01-5
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Salvianolic-acid-A
分子式：	C26H22O10
分子量：	494.44

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	粉末型式 -20°C 3年；4°C 2年溶于溶剂 -80°C 6个月；-20°C 1个月

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

23. [6.449] Chaogeng Lyu et al."A field trials-based study reveals the effects of chlormequat chloride on the quality of medicinal plant Salvia miltiorrhiza Bge. (Lamiaceae) in practical cultivation."INDUSTRIAL CROPS AND PRODUCTS.2023 Apr;194:116396

22. [IF=9.429] Zhang Bing et al."The anti-tumor and renoprotection study of E-[c(RGDfK)2]/folic acid co-modified nanostructured lipid carrier loaded with doxorubicin hydrochloride/salvianolic acid A."JOURNAL OF NANOBIOTECHNOLOGY.2022 Dec;20(1):1-20

21. [IF=3.935] Yaqing Guo et al."An integrated strategy for the systematic chemical characterization of Salvianolate lyophilized injection using four scan modes based on the ultra-high performance liquid chromatography-triple quadrupole-linear ion trap mass spectrometry.

20. [IF=9.078] Jun Qian et al."A strategy for effective recovery of salvianolic acid a from Salvia miltiorrhiza (Danshen) through multiple interactions."Compos Part B-Eng. 2022 Feb;231:109563

19. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

18. [IF=3.216] Shuang Feng et al."Salvianolic Acid A Exhibits Anti-Inflammatory and Antiarthritic Effects via Inhibiting NF-κB and p38/MAPK Pathways."Drug Des Dev Ther. 2020; 14: 1771–1778

17. [IF=2.943] Zheng Chunli et al."System-level multi-target drug discovery from natural products with applications to cardiovascular diseases."Mol Divers. 2014 Aug;18(3):621-635

16. [IF=3.049] Jixia Wang et al."Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay."Rsc Adv. 2015 Mar;5(33):25768-25776

15. [IF=4.759] Yanmei Zhang et al."Screening of mammalian target of rapamycin inhibitors in natural product extracts by capillary electrophoresis in combination with high performance liquid chromatography–tandem mass spectrometry."J Chromatogr A. 2015 Apr;1388:267

14. Zhou, Jing, et al. "A strategy for rapid discovery of traceable chemical markers in herbal products using MZmine 2 data processing toolbox: A case of Jing Liqueur." Chinese Herbal Medicines (2021).

13. Wang, Jixia, et al. "Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay." RSC Advances 5.33 (2015): 25768-25776.https://doi.org/10.1039/C4RA16102E

12. 乐世俊,王文晓,高欢,任继国,付瑞嘉,李佳佳,陈艳琰,唐于平.HPLC同时测定不同厂家丹七片中多个有效成分的含量[J].药物分析杂志,2020,40(12):2236-2243.

11. 黑小斌,李欢,李慧,梁小燕,高静,彭亮,李依民,张岗.丹参无菌培养体系构建及有效成分含量的HPLC分析[J].中草药,2020,51(22):5833-5838.

10. 王芸, 陈军峰, 张磊,等. 基于"有效成分-性状"的关联分析评价丹参品质的研究[J]. 世界科学技术:中医药现代化, 2019(5):835-843.

9. 赵志国, 段文娟, 张晓梦,等. HPLC-DAD-ESI-TOF/MS鉴别和测定前列欣胶囊中多种成分及其多指标定量指纹图谱研究[J]. 药物分析杂志, 2017, 037(010):1810-1816.

8. 李正, 潘万芳, 朱立明,等. 基于物质流分析的丹红注射液制药过程质量控制研究[J]. 天津中医药大学学报, 2015, 34(06):349-352.

7. 马东来刘爱朋林悦谢赟刘涛朱峰莉楚立.丹参有效成分与铁离子的相互作用[J].广州化工 2017 45(14):117-118+144.

6. 冯思念王瑞顾雯等. 不同强度的红蓝光质对丹参根系形态和有效成分积累的影响[J]. 中草药 2019(21).

5. 邢志华, 包然, 姜婧雯,等. 芹菜素-钐配合物的合成及其抗小鼠高尿酸血症研究. 天然产物研究与开发.

4. 黄莎莎赵文静张悦等. 中药酚酸类成分在PES膜分离过程中的透过机制研究[J]. 中国中药杂志 2020 v.45(01):114-120.

3. 彭九嫚, 柴尧, 潘旻,等. 丹参中酚酸类成分在不同工艺条件下转化关系[J]. 中国实验方剂学杂志, 2016, 022(005):67-70.

2. 姜峰李飏张敏等. 丹参中丹酚酸A转化方法[J]. 中成药 2018 40(009):2091-2096.

1. 张素清虞立范红晶等. 丹参中丹酚酸A在高温高压条件下的转化提取工艺研究[J]. 中华中医药学刊 2017 035(012):3084-3087.