党参炔苷|cas:136085-37-5|西域试剂

党参炔苷,分析标准品,HPLC≥99%

产品编号：西域质检-TM59182| CAS NO：136085-37-5| 分子式：C₂₀H₂₈O₈| 分子量：396.431

Lobetyolin 是一种分离自 Codonopsis pilosula 的生物活性化合物。Lobetyolin 具有抗炎，抗氧化和黄嘌呤氧化酶抑制活性。Lobetyolin 还通过抑制 ASCT2 介导的谷氨酰胺代谢来诱导细胞凋亡。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	价格	库存与货期
西域质检-TM59182	￥890.00	杭州北京（现货）
西域质检-TM59182	￥1500.00	杭州北京（现货）
西域质检-TM59182	￥4500.00	杭州北京（现货）

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党参炔苷

Reference Material

This certificate is designed in accordance with ISO 17034 and ISO Guide 31. This reference material (RM) was designed,produced and verified in accordance with ISO/IEC 17025, ISO 17034 and a registered quality management system ISO 9001.

Product Name(产品名称) Lobetyolin(党参炔苷)

Product Code(产品编号) 723290-10mg

Lot Number(产品批号) -

CAS No. 136085-37-5

Mol. Weight(分子量) 396.43

Mol. Formula(分子式) C₂₀H₂₈O₈

Melting Point(熔点) N/A

Expiry Date(失效日期) -

Boiling point(沸点) N/A

Appearance(外观) Yellow Solid
(黄色固体)____________

Storage Temp(存储条件) (-18±5)℃,Keep in the shade
冷冻(-18±5)℃,置于阴凉处

C E R T I F I E D

Purity

98.8%

C E R T I F I E D

Expanded Uncertainty (U)

0.8%

Uncertainty

The certified value(s) and uncertainty(ies) are determined in accordance with ISO 17034 with an 95% confidence level(k=2). Uncertainty is based on the Total Combined Uncertainty, including uncertainties of characterisation, homogeneity and stability testing. Stability values are based on real evidence opposed to simulation.

Traceability

The balances used for gravimetric measurements are calibrated with weights traceable to the national standards. The calibration of the balances is verified annually by an external accredited calibration service. This analysis method has been verified using an approach consistent with ISO 17034:2016 & ISO 17025:2017.

CERTIFICATE ON	QC SIGNATURE
-		RM Release

Method of Identification

HPLC

Method of Identification

HPLC

Intended Use

This RM is intended for use in a laboratory as a calibration and quality control standard or in method development for analytical techniques.

Storage

This reference material meets the specification stated in this certificate until the expiry date, provided it is stored unopened at the recommended temperature here in. If storage after opening is necessary, the RM should be tightly closed and kept from light and moisture.

Hazards

Read Material Safety Data Sheet (MSDS) and understand any potential hazard(s) prior to the use of this product. All chemicals should be considered potentially hazardous in nature and should only be handled by qualified personnel using established good laboratory practices.

Homogeneity

Random replicate samples of the final packaged RM have been analysed to prove homogeneity compliant with ISO 17034.

Instructions for use

It is recommended to use 1 mg as the minimum sample size and if less material is used, to increase the certified uncertainty by a factor of two for half sample and four for a quarter of sample.Visit the support section of our website technology videos and frequently asked questions.

化学品安全说明书(MSDS)

下载MSDS

质检证书(COA)

安全声明 (欧洲)	24/25

1. 物质的识别

产品名：	Lobetyolin
CAS号：	136085-37-5
制造商/供应商：	西域试剂网站：www.hzbp.cn 邮件：13911702513@139.com

2. 合成/成分数据

产品名：	Lobetyolin
分子式：	C20H28O8
分子量：	396.43

3. 急救措施

吸入后：	如果吸入，移至空气新鲜处，如果呼吸困难，给输氧，如呼吸停止，给予人工呼吸。
皮肤接触后：	用大量的水冲洗，移除污染的衣服和鞋子。
眼睛接触后：	检查并取下隐形眼镜，并用大量的水冲洗；呼叫医生。
吞食后：	如果吞食，用大量纯净水漱口；呼叫医生。

4. 消防措施

适当的灭火剂：	雾状水，二氧化碳，干粉或泡沫。
防护设备：	穿戴自给式呼吸器和防护服，以防止与皮肤和眼睛接触。

5. 泄漏应急处理

安全防范措施：	封锁泄漏区域；穿戴自给式呼吸器，防护服和厚橡胶手套。
清洁/收集措施：	使用液体粘合原料（硅藻土，通用粘合剂）吸取精细粉末；使用酒精擦洗表面和设备除去污渍；根据第11条处理被污染的材料。

6. 处理和储存

安全处理说明：	避免吸入和接触皮肤，眼睛及衣物；材料可能略微具有刺激性。
储存：	-20°C, protect from light, dry, sealed

7. 接触控制和个人防护

呼吸设备：	NIOSH / MSHA认可的呼吸器。
双手保护：	耐化学腐蚀的橡胶手套。
眼睛防护：	化学安全护目镜。

8. 稳定性和反应活性

稳定性：	按照说明存储是稳定的；避免强氧化剂。
热分解/其他要避免的情况：	避免光和热。

9. 毒性资料

急性毒性：	无可用资料。
主要刺激性影响：	无可用资料。
在皮肤上：	无可用资料。
对眼睛：	无可用资料；可能具有刺激性。

10. 生态资料

一般注意事项：

无可用资料。

11. 废弃处置

按照所在国家，省份，县市和地方的法规处置。

12. 运输信息

正确的运输名称：	无
非危险品运输：	这种物质被视为非危险品运输。

13. 法规信息

尚未有针对此产品作出的化学安全性评估。

14. 其他信息

13. [3.614] Shu-Yun Yang et al."An integrated approach of HPLC-MS-based chemical profiling, network pharmacology, and molecular docking to reveal the potential mechanisms of Qishen Gubiao Granules for treating COVID-19."JOURNAL OF SEPARATION SCIENCE.2023 Mar;:2200953

12. [IF=3.614] Jing Liu et al."Phytochemical identification of Xiaoer Huanglong Granule and pharmacokinetic study in the rat using its seven major bioactive components."JOURNAL OF SEPARATION SCIENCE

11. [IF=4.821] Xiangwei Chang et al."Untargeted metabolomics approach reveals the tissue-specific markers of balloon flower root (Platycodi Radix) using UPLC-Q-TOF/MS."Microchem J. 2021 Sep;168:106447

10. [IF=3.373] Binjun Yan et al."Root Cause Analysis of Quality Defects Using HPLC–MS Fingerprint Knowledgebase for Batch-to-batch Quality Control of Herbal Drugs."Phytochem Analysis. 2015 Jul;26(4):261-268

9. [IF=3.935] Lijuan Shen et al."Identification of bioactive ingredients with immuno-enhancement and anti-oxidative effects from Fufang-Ejiao-Syrup by LC–MSn combined with bioassays."J Pharmaceut Biomed. 2016 Jan;117:363

8. [IF=4.556] Yuanyuan Xia et al."Characterization, quantitation and similarity evaluation of Codonopsis lanceolata from different regions in China by HPLC-Q-TQF-MS and chemometrics."J Food Compos Anal. 2017 Sep;62:134

7. Xia, Yuanyuan, et al. "Characterization, quantitation and similarity evaluation of Codonopsis lanceolata from different regions in China by HPLC-Q-TQF-MS and chemometrics." Journal of Food Composition and Analysis 62 (2017): 134-142.https://doi.org/10.1016

6. Shen, Lijuan, et al. "Identification of bioactive ingredients with immuno-enhancement and anti-oxidative effects from Fufang-Ejiao-Syrup by LC–MSn combined with bioassays." Journal of pharmaceutical and biomedical analysis 117 (2016): 363-371.https://doi.o

5. 范小龙,陈冉,吴婉琴,刘国姣,黄坤,江丰.液相色谱串联质谱法测定食品中淫羊藿苷等20种功能成分[J].食品与机械,2021,37(01):86-93+98.

4. 赵娜,付瑶,张诗航,张栋,张大方.HPLC-PDA-ELSD测定参芪五味子胶囊中10个成分含量及化学模式识别研究[J].中国现代应用药学,2021,38(05):609-614.

3. 陈天朝, 王娇, 李瑞颖,等. 基于清炒法对党参物性及有效成分含量变化的研究[J]. 中国现代中药, 2019, 21(02):96-101.

2. 陈江鹏, 戴俊东, 裴纹萱,等. 基于功效成分与形性指标相关性分析的米炒党参炮制工艺标准化研究[J]. 中国中药杂志, 2018, 043(012):2543-2551.

1. 陈天朝耿梦丽常倩倩等. 党参不同炮制品丸剂溶出前后物性参数及化学成分相关性研究[J]. 中国中医药信息杂志 2020年27卷7期 81-87页 ISTIC CSCD CA 2020