PERK-IN-6
产品编号:Bellancom-153160| CAS NO:1337532-14-5| 分子式:C23H22N6O| 分子量:398.46
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PERK-IN-6
产品介绍 | PERK-IN-6 (Compound 5) 是一种 PERK 抑制剂,IC50 为 2.5 nM。 |
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生物活性 | PERK-IN-6 (Compound 5) is a PERK inhibitor with an IC50 of 2.5 nM. |
体外研究 |
在 A549 细胞中,PERK-IN-6 (Compound 5) 抑制 thapsigargin 诱导的 PERK 自磷酸化,IC50 为 0.1-0.3 μΜ。 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 |
SD 大鼠静脉注射 PERK-IN-6 (Compound 5) 后血液清除率为 10.5 mL/min/kg 。 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 |
SD 大鼠静脉注射 PERK-IN-6 (Compound 5) 后血液清除率为 10.5 mL/min/kg 。 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
性状 | |
溶解性数据 | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
参考文献 |