Bromo-PEG4-bromide|cas:57602-02-5|西域试剂

Bromo-PEG4-bromide

产品编号：Bellancom-W040527| CAS NO：57602-02-5| 分子式：C₁₀H₂₀Br₂O₄| 分子量：364.07

Bromo-PEG4-bromide 是一种 PROTAC linker，属于 PEG 类。Bromo-PEG4-bromide 可用于合成 PROTAC 分子。

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-W040527		￥350.00	杭州北京（现货）
Bellancom-W040527		￥700.00	杭州北京（现货）

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Bromo-PEG4-bromide

产品介绍

Bromo-PEG4-bromide 是一种 PROTAC linker，属于 PEG 类。Bromo-PEG4-bromide 可用于合成 PROTAC 分子。

生物活性

Bromo-PEG4-bromide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

体外研究

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Liquid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

. Mulyana Y, et al. Oligonuclear polypyridylruthenium(II) complexes incorporating flexible polar and non-polar bridges: synthesis, DNA-binding and cytotoxicity. Dalton Trans. 2011 Feb 21;40(7):1510-23. [Content Brief]

. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. [Content Brief]

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海关编码	2909199090

4792-15-8

~86%

57602-02-5

文献：Biron, Eric; Otis, Francois; Meillon, Jean-Christophe; Robitaille, Martin; Lamothe, Julie; Van Hove, Patrick; Cormier, Marie-Eve; Voyer, Normand Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 6 p. 1279 - 1290