GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2, with a pIC₅₀ of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity。

GW768505A free base has inhibition for cancer cells growth in NCI-60 panel screening.
GW768505A free base is an inhibitor of KDR and TIE2, shows potent inhibition (71–88% inhibition at 100 nM) of the tropomysin-related kinases TRKA, TRKB and TRKC.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

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