Thiol-C2-PEG2-OH,97.0%
产品编号:Bellancom-135085| CAS NO:56282-36-1| 分子式:C6H14O3S| 分子量:166.24
Thiol-C2-PEG2-OH 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。
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Thiol-C2-PEG2-OH
产品介绍 | Thiol-C2-PEG2-OH 是一种 PROTAC linker,属于 PEG 类。可用于合成 PROTAC 分子。 |
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生物活性 | Thiol-C2-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. |
体外研究 |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins 西域 has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 | |
体内研究 | |
性状 | Liquid |
溶解性数据 | |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 |
4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen) |
参考文献 |
~80% ![]() 56282-36-1 |
文献:Boden, Neville; Bushby, Richard J.; Liu, Quanying; Evans, Stephen D.; Toby; Jenkins; Knowles, Peter F.; Miles, Robert E. Tetrahedron, 1998 , vol. 54, # 38 p. 11537 - 11548 |
~84% ![]() 56282-36-1 |
文献:Asseline; Bonfils; Kurfurst; Chassignol; Roig; Thuong Tetrahedron, 1992 , vol. 48, # 7 p. 1233 - 1254 |
~% ![]() 56282-36-1 |
文献:Hutchison, James E.; Woehrle, Gerd H.; Warner, Marvin G.; Brown, Leif O. Patent: US2009/99044 A1, 2009 ; |
~% ![]() 56282-36-1 |
文献:Conte, Mauro Lo; Robb, Maxwell J.; Hed, Yvonne; Marra, Alberto; Malkoch, Michael; Hawker, Craig J.; Dondoni, Alessandro Journal of Polymer Science, Part A: Polymer Chemistry, 2011 , vol. 49, # 20 p. 4468 - 4475 |
~% ![]() 56282-36-1 |
文献:Charvet, Nicolas; Reiss, Peter; Roget, Andre; Dapuis, Alain; Gruenwald, Didier; Carayon, Sophie; Chandezon, Frederic; Livache, Thierry Journal of Materials Chemistry, 2004 , vol. 14, # 17 p. 2638 - 2642 |
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