Pomalidomide-6-OH,98.09%
产品编号：Bellancom-139540| CAS NO：1547162-44-6| 分子式：C13H11N3O5| 分子量：289.24
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Pomalidomide-6-OH
| 产品介绍 | Pomalidomide-6-OH 是一种基于 Pomalidomide 的 E3 泛素连接酶 cereblon (CRBN) 配体，用于募集 cereblon 蛋白。Pomalidomide-6-OH 可通过 linker 连接到蛋白质配体上形成 PROTAC。 | ||||||||||||
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| 生物活性 | Pomalidomide-6-OH is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-6-OH can be connected to the ligand for protein by a linker to form PROTAC. | ||||||||||||
| 体外研究 |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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| 性状 | Solid | ||||||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| 参考文献 |
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