Biotin-PFP ester
产品编号:Bellancom-119343| CAS NO:120550-35-8| 分子式:C16H15F5N2O3S| 分子量:410.36
Biotin-PFP ester 是一种 PROTAC linker,属于 alkyl/ether 类。可用于合成 PROTAC 分子。
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Biotin-PFP ester
产品介绍 | Biotin-PFP ester 是一种 PROTAC linker,属于 alkyl/ether 类。可用于合成 PROTAC 分子。 | ||||||||||||
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生物活性 | Biotin-PFP ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||
体外研究 |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
体内研究 | |||||||||||||
体内研究 | |||||||||||||
性状 | Solid | ||||||||||||
溶解性数据 | |||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
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参考文献 |
~98% ![]() 120550-35-8 |
文献:Korshun, Vladimir A.; Pestov, Nikolai B.; Nozhevnikova, Elena V.; Prokhorenko, Igor A.; Gontarev, Sergei V.; Berlin, Yuri A. Synthetic Communications, 1996 , vol. 26, # 13 p. 2531 - 2547 |
~95% ![]() 120550-35-8 |
文献:Chambers, Jennifer M.; Lindqvist, Lisa M.; Webb, Andrew; Huang, David C. S.; Savage, G. Paul; Rizzacasa, Mark A. Organic Letters, 2013 , vol. 15, # 6 p. 1406 - 1409 |
~80% ![]() 120550-35-8 |
文献:Stewart, Scott G.; Braun, Carlos J.; Polomska, Marta E.; Karimi, Mahdad; Abraham, Lawrence J.; Stubbs, Keith A. Organic and Biomolecular Chemistry, 2010 , vol. 8, # 18 p. 4059 - 4062 |
~96% ![]() 120550-35-8 |
文献:Rabinkov, A. G.; Pozdnev, V. F.; Amontov, S. V.; Kopelevich, V. M.; Gunar, V. I. Chemistry of Natural Compounds, 1989 , vol. 25, p. 350 - 353 Khimiya Prirodnykh Soedinenii, 1989 , # 3 p. 404 - 408 |
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