Gadobutrol 钆布醇; ZK 135079|cas:770691-21-9|西域试剂

Gadobutrol 钆布醇; ZK 135079,99.96%

产品编号：Bellancom-16217| CAS NO：770691-21-9| 分子式：C₁₈H₃₁GdN₄O₉| 分子量：604.71

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货号	价格	库存与货期
Bellancom-16217	￥850.00	杭州北京（现货）
Bellancom-16217	￥1200.00	杭州北京（现货）
Bellancom-16217	￥3600.00	杭州北京（现货）
Bellancom-16217	￥5500.00	杭州北京（现货）
Bellancom-16217	￥7500.00	杭州北京（现货）

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Gadobutrol 钆布醇; ZK 135079

产品介绍

Gadobutrol (Gd-DO3A-butrol; ZK 135079)是一种非离子顺磁性大环钆基造影剂，可用作磁共振成像(MRI)。

生物活性

Gadobutrol (Gd-DO3A-butrol; ZK 135079) is a nonionic paramagnetic macrocyclic gadolinium-based contrast agent that can be used for magnetic resonance imaging (MRI).

体外研究

Gadobutrol leads to a gradual decrease in cell density with increasing concentration under neutron irradiation.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay

Cell Line:	Human melanoma cell line Sk-Mel-28
Concentration:	0-30 mM
Incubation Time:	1 hour
Result:	Showed a decrease in cell density to 26% at 30 mM while to 80% with no gadobutrol under neutron irradiation.

体内研究
(In Vivo)

Gadobutrol (intravenous injection, 200 mM, once, a week) can significantly enhance intracerebroventricular cell signaling in female C57BL/6 N mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female C57BL/6 N mice, 11-13 weeks, 21-23 g)
Dosage:	200 mM
Administration:	Intravenous injection; once; a week
Result:	Enhanced cells signal in the habenula, hippocampal formation, and locus coeruleus.

体内研究

Gadobutrol (intravenous injection, 200 mM, once, a week) can significantly enhance intracerebroventricular cell signaling in female C57BL/6 N mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female C57BL/6 N mice, 11-13 weeks, 21-23 g)
Dosage:	200 mM
Administration:	Intravenous injection; once; a week
Result:	Enhanced cells signal in the habenula, hippocampal formation, and locus coeruleus.

体内研究

Gadobutrol (intravenous injection, 200 mM, once, a week) can significantly enhance intracerebroventricular cell signaling in female C57BL/6 N mice.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female C57BL/6 N mice, 11-13 weeks, 21-23 g)
Dosage:	200 mM
Administration:	Intravenous injection; once; a week
Result:	Enhanced cells signal in the habenula, hippocampal formation, and locus coeruleus.

性状

Solid

溶解性数据

In Vitro:

H₂O : 20 mg/mL (33.07 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.6537 mL	8.2684 mL	16.5369 mL
5 mM	0.3307 mL	1.6537 mL	3.3074 mL
10 mM	0.1654 mL	0.8268 mL	1.6537 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶