YSK 05,98.0%
产品编号：Bellancom-147087| CAS NO：1318793-78-0| 分子式：C42H77NO2| 分子量：628.07
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YSK 05
| 产品介绍 | YSK 05 是一种 pH 敏感的阳离子脂质。YSK 05 可改善非病毒载体的胞内转运。YSK 05-MEND 表现出明显良好的基因沉默活性和溶血活性。YSK 05 通过聚乙二醇化克服了对内体逃逸的抑制。YSK 05 在体外和体内均有效增强 siRNA 传递。 | ||||||||||||
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| 生物活性 | YSK 05 is a pH-sensitive cationic lipid. YSK 05 improves the intracellular trafficking of non-viral vectors. YSK 05-MEND shows significantly good gene silencing activity and hemolytic activity. YSK 05 overcomes the suppression of endosomal escape by PEGylation. YSK 05 effectively enhances siRNA delivery both in vitro and in vivo. | ||||||||||||
| 体外研究 |
YSK 05 facilitates the endosomal escape of the MEND and thereby enhances the efficacy of siRNA delivery into cytosol and gene silencing. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||
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| 性状 | Liquid | ||||||||||||
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| 参考文献 |
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