Ropidoxuridine IPdR,99.78%
产品编号:Bellancom-13742| CAS NO:93265-81-7| 分子式:C9H11IN2O4| 分子量:338.10
Ropidoxuridine (IPdR) 是一种新型口服,卤化胸苷类似物,有希望用于人类肿瘤的增敏剂。
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Ropidoxuridine IPdR
| 产品介绍 | Ropidoxuridine (IPdR) 是一种新型口服,卤化胸苷类似物,有希望用于人类肿瘤的增敏剂。 | ||||||||||||||||
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| 生物活性 | Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors. | ||||||||||||||||
| 体外研究 |
Ropidoxuridine is an orally bioavailable pro-drug of IUdR (5-iodo-2'-deoxyuridine). Ropidoxuridine demonstrates strong synergy effects with Alisertib at clinically relevant concentrations. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
| 体内研究 |
In an orthotopic tumor model, Ropidoxuridine (750 mg/kg/day) and Alisertib (30 mg/kg/day) demonstrate strong synergy effects. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
| 体内研究 |
In an orthotopic tumor model, Ropidoxuridine (750 mg/kg/day) and Alisertib (30 mg/kg/day) demonstrate strong synergy effects. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
| 性状 | Solid | ||||||||||||||||
| 溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (739.43 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百 *以上所有助溶剂都可在 西域 网站选购。
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
| 储存方式 |
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| 参考文献 | |||||||||||||||||
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~45%
93265-81-7 |
| 文献:Efange, Simon M. N.; Alessi, Elaine M.; Shih, H. C.; Cheng, Yung-Chi; Bardos, Thomas J. Journal of Medicinal Chemistry, 1985 , vol. 28, # 7 p. 904 - 910 |
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