Azithromycin-d3 阿奇霉素 13C-d3|cas:163921-65-1|西域试剂

Azithromycin-d₃ 阿奇霉素 ¹³C-d₃,95.0%

产品编号：Bellancom-17506S| CAS NO：163921-65-1| 分子式：C₃₈H₆₉D₃N₂O₁₂| 分子量：752.00

阿奇霉素d3（CP 62993-d3）是氘标记的阿奇霉素。阿奇霉素（CP-62993）是一种大环内酯类抗生素，可用于治疗多种细菌感染。

本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断或者治疗,非药用,非食用，

货号	包装	价格	库存与货期	购买量	操作
Bellancom-17506S		￥4300.00	杭州北京（现货）

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Azithromycin-d₃ 阿奇霉素 ¹³C-d₃

产品介绍

Azithromycin-d₃ 是 Azithromycin 的氘代物。Azithromycin (CP-62993) 是一种大环内酯抗生素，常用于细菌感染的研究。

生物活性

Azithromycin-d₃ is the deuterium labeled Azithromycin. Azithromycin (CP-62993) is a macrolide antibiotic useful for the treatment of a number of bacterial infections.

体外研究

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

. Menzel M, et al. Azithromycin augments rhinovirus-induced IFNβ via cytosolic MDA5 in experimental models of asthma exacerbation. Oncotarget. 2017 Mar 18. [Content Brief]

. Vandooren J, et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib: A comparative study. PLoS One. 2017 Apr 3;12(4):e0174853. [Content Brief]

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Azithromycin-d3 阿奇霉素 13C-d3,95.0%