Tramiprosate-d6 Homotaurine-d6; 3-Amino-1-propanesulfonic acid-d6|cas:1131576-06-1|西域试剂

Tramiprosate-d₆ Homotaurine-d₆; 3-Amino-1-propanesulfonic acid-d₆,98.0%

产品编号：Bellancom-14602S| CAS NO：1131576-06-1| 分子式：C₃H₃D₆NO₃S| 分子量：145.21

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Tramiprosate-d₆ Homotaurine-d₆; 3-Amino-1-propanesulfonic acid-d₆

产品介绍

Tramiprosate-d₆ 是 Tramiprosate 的氘代物。Tramiprosate (Homotaurine)，一种具有口服活性和可透过血脑屏障的天然氨基酸，存在于各种红色海藻中。Tramiprosate 与可溶性 Aβ 结合并以非原纤维形式维持 Aβ。Tramiprosate 还是一种 GABA 类似物，具有神经保护，抗惊厥和抗高血压的作用。

生物活性

Tramiprosate-d₆ is the deuterium labeled Tramiprosate. Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects.

体外研究

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

H₂O : 50 mg/mL (344.33 mM; ultrasonic and warming and heat to 60°C)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	6.8866 mL	34.4329 mL	68.8658 mL
5 mM	1.3773 mL	6.8866 mL	13.7732 mL
10 mM	0.6887 mL	3.4433 mL	6.8866 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式