Deoxylimonin|cas:989-23-1|西域试剂

Deoxylimonin,99.49%

产品编号：Bellancom-N7640| CAS NO：989-23-1| 分子式：C₂₆H₃₀O₇| 分子量：454.51

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-N7640		￥1400.00	杭州北京（现货）

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Deoxylimonin

产品介绍

Desoxylimonin 是一种具有口服活性的三萜类化合物，可从葡萄柚种子中发现。Desoxylimonin 对乳腺癌细胞有抗增殖活性，其衍生物显示出更好的抗癌、镇痛和抗炎活性。

生物活性

Desoxylimonin is an orally active triterpenoid compound found from grapefruit seed. Desoxylimonin shows anti-proliferative activities to breast cancer cells. Desoxylimonin derivatives shows better anticancer, analgesic and anti-inflammatory activity than the lead compound.

体外研究

Deoxylimonin (0-90 μg/mL, 48 h) treatment shows anti-proliferation activities to breast cancer cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay

Cell Line:	MDA-MB-435 and MCF-7 cells
Concentration:	0-90 μg/mL
Incubation Time:	48 hours
Result:	Showed IC₅₀ values of 0.78 μg/mL and 2.50 μg/mL for MDA-MB-435 and MCF-7 cells, respectively.

体内研究
(In Vivo)

Deoxylimonin (oral administration; 70 mg/kg; once) treatment shows antinociception effects in vivo.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Mice injected with acetic acid
Dosage:	70 mg/kg
Administration:	Oral administration; 70 mg/kg; once
Result:	Showed the antinociception efficacy (writhing inhibition rate: 24.61%).

体内研究

Deoxylimonin (oral administration; 70 mg/kg; once) treatment shows antinociception effects in vivo.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Mice injected with acetic acid
Dosage:	70 mg/kg
Administration:	Oral administration; 70 mg/kg; once
Result:	Showed the antinociception efficacy (writhing inhibition rate: 24.61%).

体内研究

Deoxylimonin (oral administration; 70 mg/kg; once) treatment shows antinociception effects in vivo.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Mice injected with acetic acid
Dosage:	70 mg/kg
Administration:	Oral administration; 70 mg/kg; once
Result:	Showed the antinociception efficacy (writhing inhibition rate: 24.61%).

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (220.02 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.2002 mL	11.0009 mL	22.0017 mL
5 mM	0.4400 mL	2.2002 mL	4.4003 mL
10 mM	0.2200 mL	1.1001 mL	2.2002 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献