Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE|cas:1638970-46-3|西域试剂

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

产品编号：Bellancom-147204| CAS NO：1638970-46-3| 分子式：C₆₇H₁₀₁N₁₁O₁₆| 分子量：1316.58

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-147204		￥7800.00	杭州北京（现货）
Bellancom-147204		￥12500.00	杭州北京（现货）

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Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE

产品介绍

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) 是一种有效的抗癌剂 (anticancer agent)，它可被肿瘤微环境特异性激活。Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE 可抑制小鼠肿瘤生长 (信息来自专利 CN104147612A)。

生物活性

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) is a potent anticancer agent, which can be specific activated by tumor microenvironment. Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE can suppress tumor growth in mice (extracted from patent CN104147612A).

体外研究

体内研究

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) (26.2 micro-rubbing/kg, IV, weekly for 4 weeks) suppresses tumor growth in mice bearing Panc-1 tumor.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE (compound S6) (26.2 micro-rubbing/kg, IV, weekly for 4 weeks) suppresses tumor growth in mice bearing Panc-1 tumor.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

DMSO : 180 mg/mL (136.72 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.7595 mL	3.7977 mL	7.5954 mL
5 mM	0.1519 mL	0.7595 mL	1.5191 mL
10 mM	0.0760 mL	0.3798 mL	0.7595 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

参考文献