Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab is also an angiogenesis inhibitor.

Ramucirumab (10 μg/mL) impedes both VEGF- and tumor-driven cord formation.
Ramucirumab does not cross react with mouse VEGFR2.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

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