Sappanchalcone|cas:94344-54-4|西域试剂

Sappanchalcone,99.62%

产品编号：Bellancom-59001| CAS NO：94344-54-4| 分子式：C₁₆H₁₄O₅| 分子量：286.28

Sapanchalcone，一种从苏木中分离的黄酮类化合物，诱导人结肠癌细胞中的caspase依赖性和AIF依赖性凋亡。

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-59001		￥3500.00	杭州北京（现货）
Bellancom-59001		￥9800.00	杭州北京（现货）

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Sappanchalcone

产品介绍

Sappanchalcone 从 Caesalpinia sappan L. 中提取的黄酮类化合物，诱导人结肠癌细胞凋亡 (apoptosis)。

生物活性

Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells.

体外研究

Sappanchalcone has a statistically significant effect on HCT116 cells than on SW480 cells (IC₅₀= 37.33 μM and 54.23 μM, respectively). Sappanchalcone reduces MMP with a significant increase in ROS levels in human colon cancer cells. Sappanchalcone triggered phosphorylation of p53, which is involved in the activation of caspases and increased expression of Bax in HCT116 cells.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

. Seo HW, et al. Sappanchalcone, a flavonoid isolated from Caesalpinia sappan L., induces caspase-dependent and AIF-dependent apoptosis in human colon cancer cells. Chem Biol Interact. 2020;327:109185. [Content Brief]

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Sappanchalcone,99.62%

Sappanchalcone

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