Dusquetide SGX942|cas:931395-42-5|西域试剂

Dusquetide SGX942,99.10%

产品编号：Bellancom-P2076| CAS NO：931395-42-5| 分子式：C₂₅H₄₇N₉O₅| 分子量：553.70

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货号	价格	库存与货期
Bellancom-P2076	￥2200.00	杭州北京（现货）
Bellancom-P2076	￥5600.00	杭州北京（现货）
Bellancom-P2076	￥9500.00	杭州北京（现货）

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Dusquetide SGX942

产品介绍

Dusquetide (SGX942) 是第一类天然防御调节因子 (IDR)。Dusquetide 通过与 p62 结合调节 PAMPs 和 DAMPs 的天然免疫应答。Dusquetide 在减轻炎症和增加细菌感染清除方面都显示出活性。

生物活性

Dusquetide (SGX942) is a first-in-class innate defense regulator (IDR). Dusquetide modulates the innate immune response to both PAMPs and DAMPs by binding to p62. Dusquetide shows activity in both reducing inflammation and increasing clearance of bacterial infection. DAMPs: damage-associated molecular patterns; PAMPs: pathogen-associated molecular patterns

体外研究

体内研究

Dusquetide (SGX942) (25 mg/kg; i.v.; days 0, 4, 7, 10, and 14) shows no increase in tumor growth or worsening of survival and a trend towards decreased tumor growth and improvement in survival with radiation.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female nude mice (MCF-7 tumor xenografts)
Dosage:	25 mg/kg
Administration:	I.v.; days 0, 4, 7, 10, and 14
Result:	Showed no increase in tumor growth or worsening of survival and a trend towards decreased tumor growth and improvement in survival with radiation.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Female nude mice (MCF-7 tumor xenografts)
Dosage:	25 mg/kg
Administration:	I.v.; days 0, 4, 7, 10, and 14
Result:	Showed no increase in tumor growth or worsening of survival and a trend towards decreased tumor growth and improvement in survival with radiation.

性状

Solid

溶解性数据

In Vitro:

H₂O : 50 mg/mL (90.30 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.8060 mL	9.0302 mL	18.0603 mL
5 mM	0.3612 mL	1.8060 mL	3.6121 mL
10 mM	0.1806 mL	0.9030 mL	1.8060 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture and light, under nitrogen