7-keto-Deoxycholic acid 7-酮-3α,12-α-二羟基胆酸|cas:911-40-0|西域试剂

7-keto-Deoxycholic acid 7-酮-3α,12-α-二羟基胆酸,98.32%

产品编号：Bellancom-41324| CAS NO：911-40-0| 分子式：C₂₄H₃₈O₅| 分子量：406.56

7-酮-石胆酸是绝对梭菌中胆汁酸的代谢物。7-酮-石胆酸也在特定条件下由乳酸杆菌和双歧杆菌转化。

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货号	价格	库存与货期
Bellancom-41324	￥900.00	杭州北京（现货）
Bellancom-41324	￥2600.00	杭州北京（现货）
Bellancom-41324	￥4000.00	杭州北京（现货）

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7-keto-Deoxycholic acid 7-酮-3α,12-α-二羟基胆酸

产品介绍

7-keto-lithocholic acid 是胆酸在 Clostridium absonum 中的代谢产物。7-keto-lithocholic acid 也可由乳酸杆菌和双歧杆菌在特定条件下也可转化得到。

生物活性

7-keto-lithocholic acid is a metabolite of bile acids in Clostridium absonum. 7-keto-lithocholic acid is also converted from Lactobacillus and Bifidobacterium with specific condition.

体外研究

7-keto-lithocholic acid shows an increasing bioconversion rate with addition of an equimolar concentration of deoxycholic acid (which itself is not metabolized).
7-keto-lithocholic acid is induced by deoxycholic acid and then it's metabolized.
E. lentum-like c-25 converts 81.7% of 2 mM cholic acid to deoxycholic acid and 3.7% to 7-keto-deoxycholic acid under anaerobic incubation.
E. lentum-like c-25 converts 91.5% of 150 mg/mL cholic acid to deoxycholic acid and 1.1% to 7-keto-deoxycholic acid under anaerobic incubation.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (245.97 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	2.4597 mL	12.2983 mL	24.5966 mL
5 mM	0.4919 mL	2.4597 mL	4.9193 mL
10 mM	0.2460 mL	1.2298 mL	2.4597 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献