Crosstide|cas:171783-05-4|西域试剂

Crosstide,99.48%

产品编号：Bellancom-P0315| CAS NO：171783-05-4| 分子式：C₄₈H₇₇N₁₇O₁₇| 分子量：1164.23

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-P0315		￥1100.00	杭州北京（现货）
Bellancom-P0315		￥4400.00	杭州北京（现货）

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Crosstide

产品介绍

Crosstide 是一种糖原合成酶激酶α/β融合蛋白序列的模拟肽，是 Akt 的底物。

生物活性

Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt.

体外研究

16HBE14o− cells exposed to RV39 demonstrate a crosstide kinase activity in vitro. Serine phosphorylation of crosstide is confirmed by immunoblotting, and phosphorylation is blocked by PP2 but not by PP3. The wildtype GST-AKT2 shows significant phosphoryl transferase activity towards crosstide, reaching an initial velocity of 16 pmol phosphate/min/μg enzyme. The mutant GST-AKT2T/E,S/D displayed an initial velocity of 85 pmol phosphate/min/μg kinase for phosphorylation of Crosstide, corresponding to a 5-fold increase compared to the wildtype enzyme.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

H₂O : ≥ 50 mg/mL (42.95 mM)

* "≥" means soluble, but saturation unknown.

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	0.8589 mL	4.2947 mL	8.5894 mL
5 mM	0.1718 mL	0.8589 mL	1.7179 mL
10 mM	0.0859 mL	0.4295 mL	0.8589 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture