4-Hydroxymephenytoin-d<sub>3</sub>|cas:1173022-56-4|西域试剂

4-Hydroxymephenytoin-d₃,98.73%

产品编号：Bellancom-W008772S| CAS NO：1173022-56-4| 分子式：C₁₂H₁₁D₃N₂O₃| 分子量：237.27

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-W008772S		￥8800.00	杭州北京（现货）

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4-Hydroxymephenytoin-d₃

产品介绍

4-Hydroxymephenytoin-d₃ 是 4-Hydroxymephenytoin 的氘代物。4-Hydroxymephenytoin 是抗癫痫剂 mephenytoin 的代谢物; mephenytoin 为 CYP2C19 的一种配体。

生物活性

4-Hydroxymephenytoin-d₃ is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic agent mephenytoin, which is used as a CYP2C19 substrate.

体外研究

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

性状

Solid

溶解性数据

In Vitro:

DMSO : 100 mg/mL (421.46 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.2146 mL	21.0730 mL	42.1461 mL
5 mM	0.8429 mL	4.2146 mL	8.4292 mL
10 mM	0.4215 mL	2.1073 mL	4.2146 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式