N'-Nitro-D-arginine|cas:66036-77-9|西域试剂

N'-Nitro-D-arginine

产品编号：Bellancom-W014049| CAS NO：66036-77-9| 分子式：C₆H₁₃N₅O₄| 分子量：219.20

N’-硝基-D-精氨酸（NOLA）是一种一氧化氮合成抑制剂，也是一种血管舒张剂，可松弛平滑肌，增加流向阴茎的血流，改善勃起。N'-硝基-D-精氨酸还通过阻断肿瘤坏死因子α（TNFα）和白细胞介素8（IL8）受体来抑制中性粒细胞迁移。

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-W014049		￥350.00	杭州北京（现货）
Bellancom-W014049		￥560.00	杭州北京（现货）

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N'-Nitro-D-arginine

产品介绍

N'-Nitro-D-arginine，一氧化氮合成抑制剂，也是一种血管扩张剂，可以放松平滑肌，增加血液流向阴茎，改善勃起。N'-Nitro-D-arginine 也被证明可以通过阻断肿瘤坏死因子 α (TNFα) 和白细胞介素 8 (IL8) 的受体来抑制中性粒细胞的迁移。

生物活性

N'-Nitro-D-arginine, a nitric oxide synthesis inhibitor, also is a vasodilator that relaxes the smooth muscles and increases blood flow to the penis, improving erections. N'-Nitro-D-arginine also inhibits neutrophil migration by blocking receptors for tumour necrosis factor alpha (TNFα) and interleukin 8 (IL8).

体外研究

体内研究

N'-Nitro-D-arginine (40 mg/kg) produces a significant increase in systolic blood pressure in the chronic, awake, instrumented sheep model.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

N'-Nitro-D-arginine (40 mg/kg) produces a significant increase in systolic blood pressure in the chronic, awake, instrumented sheep model.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

. C K Narkowicz, et al. Delayed recovery from NG-nitro-L-arginine in the conscious sheep. Clin Exp Pharmacol Physiol. 1991 Dec;18(12):843-6. [Content Brief]

化学品安全说明书(MSDS)

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质检证书(COA)

产品编号(Item Number)

批号(Lot Number)

相关产品

危害码 (欧洲)	Xn
风险声明 (欧洲)	22-36/37/38
安全声明 (欧洲)	26-36
海关编码	2925290090

Material Safety Data Sheet

Section1. Identiﬁcation of the substance
Product Name: H-D-Arg(No2)-OH
Synonyms:

Section2. Hazards identiﬁcation
Harmful by inhalation, in contact with skin, and if swallowed.

Section3. Composition/information on ingredients.
Ingredient name:H-D-Arg(No2)-OH
CAS number:66036-77-9

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
ﬂushing of the eyes by separating the eyelids with ﬁngers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire ﬁghting measures
In the event of a ﬁre involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualiﬁed
in the handling and use of potentially hazardous chemicals, who should take into account the ﬁre,
health and chemical hazard data given on this sheet.
Store in closed vessels.
Storage:

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Appearance:Not speciﬁed
Boiling point:No data
No data
Melting point:
Flash point:No data
Density:No data
Molecular formula:C6H13N5O4
Molecular weight:219.2

Section10. Stability and reactivity
Conditions to avoid: Heat, ﬂames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.

SECTION 16 - ADDITIONAL INFORMATION
N/A

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[1]. C K Narkowicz, et al. Delayed recovery from NG-nitro-L-arginine in the conscious sheep. Clin Exp Pharmacol Physiol. 1991 Dec;18(12):843-6.

N'-Nitro-D-arginine

N'-Nitro-D-arginine

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