多杀菌素,Spinosad,97%
产品编号:西域试剂-138800| CAS NO:168316-95-8| 分子式:C83H132N2O20| 分子量:1477.94
多杀菌素是一种由多杀菌素a和D组成的混合物,被称为土壤放线菌(Saccharopolyspora spinosa)的发酵产物,是一种作用谱更广的生物神经毒性杀虫剂。多杀菌素以昆虫神经系统的烟碱乙酰胆碱受体(nAChRs)为靶标。多杀菌素具有良好的环境和哺乳动物毒理学特性。杀幼虫活性。
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多杀菌素
产品介绍 | Spinosad 是一种具有更广泛作用谱的生物神经毒性杀虫剂,是一种由 spinosyns A 和 D混合而成的,是土壤放线菌发酵产物。Spinosad 靶向昆虫神经系统的烟碱乙酰胆碱受体 (nAChRs)。Spinosad 具有优良的环境和哺乳动物毒理学特征。具有杀灭幼虫的活性。 | ||||||||||||||||
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生物活性 | Spinosad, a mixture of spinosyns A and D known as fermentation products of a soil actinomycete (Saccharopolyspora spinosa), is a biological neurotoxic insecticide with a broader action spectrum. Spinosad targets the nicotinic acetylcholine receptor (nAChRs) of the insect nervous system. Spinosad has an excellent environmental and mammalian toxicological profile. Larvicidal activity. | ||||||||||||||||
体外研究 |
Spinosad acts as an allosteric agonist of acetylcholine (Ach) by binding to nicotinicacetylcholine receptors (nAChRs), prototypicalunits that function as neurotransmitter ligand-gated ion channels[4]. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
体内研究 |
Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. Spinosad 0.9% mainly interferes with nicotinic acetylcholine receptors in insects, thereby producing neuronal excitation that results in paralysis of lice from neuromuscular fatigue after extended periods of hyperexcitation. Spinosad 0.9% kills both permethrin-susceptible and permethrin-resistant populations of lice. It is also ovicidal, killing both eggs (nits) and lice[5]. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
体内研究 |
Spinosad is a natural mixture of the pediculicidal tetracyclic macrolides spinosyn A and spinosyn D. Spinosad 0.9% mainly interferes with nicotinic acetylcholine receptors in insects, thereby producing neuronal excitation that results in paralysis of lice from neuromuscular fatigue after extended periods of hyperexcitation. Spinosad 0.9% kills both permethrin-susceptible and permethrin-resistant populations of lice. It is also ovicidal, killing both eggs (nits) and lice[5]. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
性状 | Solid | ||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 10 mg/mL (6.77 mM; ultrasonic and warming and heat to 60°C) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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参考文献 |
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符号 |
![]() GHS09 |
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信号词 | Warning |
危害声明 | H410 |
警示性声明 | P273-P391-P501 |
个人防护装备 | Eyeshields;Gloves |
危害码 (欧洲) | N |
风险声明 (欧洲) | 50/53 |
安全声明 (欧洲) | 61 |
危险品运输编码 | UN3077 9/PG 3 |

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