7-BIA,98.0%
产品编号:Bellancom-115496| CAS NO:1313403-49-4| 分子式:C15H18O6| 分子量:294.30
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7-BIA
产品介绍 | 7-BIA 是一种受体型蛋白酪氨酸磷酸酶 D (PTPRD) 抑制剂,IC50 值约为 1-3 μM。 | ||||||||||||||||
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生物活性 | 7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with an IC50 of ~1-3 μM. | ||||||||||||||||
体外研究 |
7-BIA (7-butoxy illudalic acid analog) inhibits recombinant human PTPRD and recombinant human PTPRS with IC50 values of ~1–3 μM and 40 μM, respectively. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
体内研究 |
7-BIA (10-20 mg/kg; given i.p.; only once) reduces cocaine self-administration in highly experienced WT mice. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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体内研究 |
7-BIA (10-20 mg/kg; given i.p.; only once) reduces cocaine self-administration in highly experienced WT mice. 西域 has not independently confirmed the accuracy of these methods. They are for reference only.
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性状 | Solid | ||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 125 mg/mL (424.74 mM; Need ultrasonic) Ethanol : 50 mg/mL (169.89 mM; Need ultrasonic) 配制储备液
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请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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参考文献 |