(RS)-MCPG alpha-MCPG|cas:146669-29-6|西域试剂

(RS)-MCPG alpha-MCPG,99.05%

产品编号：Bellancom-100371| CAS NO：146669-29-6| 分子式：C₁₀H₁₁NO₄| 分子量：209.20

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货号	价格	库存与货期
Bellancom-100371	￥690.00	杭州北京（现货）
Bellancom-100371	￥950.00	杭州北京（现货）
Bellancom-100371	￥2100.00	杭州北京（现货）
Bellancom-100371	￥3700.00	杭州北京（现货）
Bellancom-100371	￥6800.00	杭州北京（现货）

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(RS)-MCPG alpha-MCPG

产品介绍

(RS)-MCPG (alpha-MCPG) 是一种竞争性和选择性 I/II 组代谢型谷氨酸受体 (mGluR) 拮抗剂。(RS)-MCPG 阻断 TBS 诱导的幼年和新生大鼠海马神经元的转变。

生物活性

(RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons.

体外研究

MCPG can block group I (mGluR1 and mGluR5) and group II receptors (mGluR2 and mGluR3).

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

(RS)-MCPG (alpha-MCPG; 500 μM) blocks the TBS-induced shifts in EGABA in either juvenile or neonatal neurons.
Pretreatment with the low dose of (RS)-MCPG (25 nM; i.c.; daily; 5 days) significantly attenuates amphetamine-induced locomotor activity in 10-day-old male and female rats of Sprague-Dawley descent.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

性状

Solid

溶解性数据

In Vitro:

1M NaOH : 100 mg/mL (478.01 mM; ultrasonic and adjust pH to 10 with NaOH)

DMSO : 6 mg/mL (28.68 mM; Need ultrasonic and warming)

H₂O : < 0.1 mg/mL (ultrasonic;heat to 80°C) (insoluble)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	4.7801 mL	23.9006 mL	47.8011 mL
5 mM	0.9560 mL	4.7801 mL	9.5602 mL
10 mM	0.4780 mL	2.3901 mL	4.7801 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式