DPDPE|cas:88373-73-3|西域试剂

DPDPE,98.64%

产品编号：Bellancom-P1334| CAS NO：88373-73-3| 分子式：C₃₀H₃₉N₅O₇S₂| 分子量：645.79

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货号	包装	价格	库存与货期	购买量	操作
Bellancom-P1334		￥1000.00	杭州北京（现货）
Bellancom-P1334		￥2800.00	杭州北京（现货）

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DPDPE

产品介绍

DPDPE 是一种阿片肽，是一种具有抗惊厥作用的选择性阿片受体 (DOR) 激动剂。

生物活性

DPDPE, an opioid peptide, is a selective δ-opioid receptor (DOR) agonist with anticonvulsant effects.

体外研究

体内研究

DPDPE (70 or 140 nM; i.c.v.; once) shows anticonvulsant effects in rats.
DPDPE (0.78–25 μg/mouse; i.c.v.; once) enhances bicuculline-induced convulsions in mouse.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Sprague-Dawley rats (225-275 g)
Dosage:	70 or 140 nM followed by a 2 μl saline flush
Administration:	Intracerebroventricular injection
Result:	Resulted in a significant, dose-dependent increase in the convulsive threshold to flurothyl.

Animal Model:	Male ddY mice weighing 20–30 g, pretreated with 1.5 mg/kg bicuculline (subcutaneous injection).
Dosage:	0.78–25 μg/mouse, once
Administration:	Intracerebroventricular injection
Result:	Caused a dose-dependent increase in the proportion of mice exhibiting convulsions.

体内研究

DPDPE (70 or 140 nM; i.c.v.; once) shows anticonvulsant effects in rats.
DPDPE (0.78–25 μg/mouse; i.c.v.; once) enhances bicuculline-induced convulsions in mouse.

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male Sprague-Dawley rats (225-275 g)
Dosage:	70 or 140 nM followed by a 2 μl saline flush
Administration:	Intracerebroventricular injection
Result:	Resulted in a significant, dose-dependent increase in the convulsive threshold to flurothyl.

Animal Model:	Male ddY mice weighing 20–30 g, pretreated with 1.5 mg/kg bicuculline (subcutaneous injection).
Dosage:	0.78–25 μg/mouse, once
Administration:	Intracerebroventricular injection
Result:	Caused a dose-dependent increase in the proportion of mice exhibiting convulsions.

性状

Solid

溶解性数据

In Vitro:

H₂O : 10 mg/mL (15.48 mM; Need ultrasonic)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	1.5485 mL	7.7425 mL	15.4849 mL
5 mM	0.3097 mL	1.5485 mL	3.0970 mL
10 mM	0.1548 mL	0.7742 mL	1.5485 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C 储存时，请在 6 个月内使用，-20°C 储存时，请在 1 个月内使用。

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture