Pericyazine Propericiazine; RP 8909,99.96%
产品编号:Bellancom-14263| CAS NO:2622-26-6| 分子式:C21H23N3OS| 分子量:365.49
Pericyazine (Propericiazine) 是第一代抗精神病药物,被用作短期管理严重焦虑状态和精神病的辅助药物。Pericyazine (Propericiazine) 是一种选择性的 D2 多巴胺受体 (D2-dopamine receptor) 拮抗剂。
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Pericyazine Propericiazine; RP 8909
产品介绍 | Pericyazine (Propericiazine) 是第一代抗精神病活性分子,被用作短期管理严重焦虑状态和精神病的辅助活性分子。Pericyazine (Propericiazine) 是一种选择性的 D2 多巴胺受体 (D2-dopamine receptor) 拮抗剂。Pericyazine 具有肾上腺溶解、抗胆碱能和锥体外系作用。 | ||||||||||||||||
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生物活性 | Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis. Pericyazine is a selective D2-dopamine receptor antagonist. Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects[4]. | ||||||||||||||||
体外研究 | |||||||||||||||||
体内研究 |
Studies in rodents show that Pericyazine is able to produce potentiation of ether and hexobarbital narcosis and morphine analgesia. It also has hypothermic activity and produces depression of spontaneous motor activity in mice. On a milligram potency basis, Pericyazine is more potent than chlorpromizine in the potentiation of barbiturate narcosis test and the blocking of conditioned avoidance in rats. Pericyazine demonstrates analgesic properties similar to methotrimeprazine in mice and rats and produces adrenergic blocking effects in mice and dogs[4]. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
体内研究 |
Studies in rodents show that Pericyazine is able to produce potentiation of ether and hexobarbital narcosis and morphine analgesia. It also has hypothermic activity and produces depression of spontaneous motor activity in mice. On a milligram potency basis, Pericyazine is more potent than chlorpromizine in the potentiation of barbiturate narcosis test and the blocking of conditioned avoidance in rats. Pericyazine demonstrates analgesic properties similar to methotrimeprazine in mice and rats and produces adrenergic blocking effects in mice and dogs[4]. 西域 has not independently confirmed the accuracy of these methods. They are for reference only. | ||||||||||||||||
性状 | Solid | ||||||||||||||||
溶解性数据 |
In Vitro:
DMSO : 250 mg/mL (684.01 mM; Need ultrasonic) 配制储备液
*
请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo:
请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照 In Vitro 方式配制澄清的储备液,再依次添加助溶剂:
——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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参考文献 |
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危害码 (欧洲) | Xn: Harmful; |
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风险声明 (欧洲) | R22 |
海关编码 | 2934300000 |

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