Phycocyanobilin 藻青素；藻蓝素|cas:20298-86-6|西域试剂

Phycocyanobilin 藻青素；藻蓝素,99.0%

产品编号：Bellancom-130750| CAS NO：20298-86-6| 分子式：C₃₃H₃₈N₄O₆| 分子量：586.68

Phycocyanobilin是一种口服活性抗氧化剂，是多种活性氧的有效清除剂。藻蓝蛋白可用于阿尔茨海默病的研究。

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货号	价格	库存与货期
Bellancom-130750	￥600.00	杭州北京（现货）
Bellancom-130750	￥950.00	杭州北京（现货）
Bellancom-130750	￥1800.00	杭州北京（现货）

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Phycocyanobilin 藻青素；藻蓝素

产品介绍

Phycocyanobilin 是一种具有口服活性的抗氧化剂 (reactive oxygen species)，是一种有效的活性氧清除剂。Phycocyanobilin 可用于阿尔茨海默病的研究。

生物活性

Phycocyanobilin, an orally active antioxidative agent, is an effective scavenger for various reactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease.

体外研究

Phycocyanobilin (100 μM; 0-250 min) 抑制亚油酸甲酯的过氧化，并产生较长的诱导期。
Phycocyanobilin (1 mM; 0-300 min) 抑制脂质体的氧化。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究

Phycocyanobilin (15 mg/kg; p.o.; in diet for 2 weeks) 在 2 型糖尿病小鼠中显示抗氧化作用。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male C57BL/Ks J db/db mice, a rodent model for type 2 diabetes
Dosage:	15 mg/kg
Administration:	In diet for 2 weeks
Result:	Significantly decreased blood glucose levels. Normalized the increases in urinary 8-OHdG and 8-epi-PGF_2α levels, renal oxidative stress markers evaluated by renal 8-OHdG staining and DHE staining, Nox4 mRNA, and protein expression, as well as the mRNA levels of other NAD(P)H oxidase components, inflammatory markers and HO-1.

体内研究

Phycocyanobilin (15 mg/kg; p.o.; in diet for 2 weeks) 在 2 型糖尿病小鼠中显示抗氧化作用。

西域 has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Male C57BL/Ks J db/db mice, a rodent model for type 2 diabetes
Dosage:	15 mg/kg
Administration:	In diet for 2 weeks
Result:	Significantly decreased blood glucose levels. Normalized the increases in urinary 8-OHdG and 8-epi-PGF_2α levels, renal oxidative stress markers evaluated by renal 8-OHdG staining and DHE staining, Nox4 mRNA, and protein expression, as well as the mRNA levels of other NAD(P)H oxidase components, inflammatory markers and HO-1.

性状

Solid

溶解性数据

In Vitro:

DMSO : < 1 mg/mL (ultrasonic;heat to 60°C) (insoluble or slightly soluble)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

参考文献

. Hirata T, et al. Antioxidant activities of phycocyanobilin prepared from Spirulina platensis. Journal of Applied Phycology, 2000, 12: 435-439.

. Matamoros BP, et al. Nutraceutical and therapeutic potential of Phycocyanobilin for treating Alzheimer's disease. J Biosci. 2021;46:42. [Content Brief]

. Zheng J, et al. Phycocyanin and phycocyanobilin from Spirulina platensis protect against diabetic nephropathy by inhibiting oxidative stress. Am J Physiol Regul Integr Comp Physiol. 2013 Jan 15;304(2):R110-20. [Content Brief]

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Phycocyanobilin 藻青素；藻蓝素,99.0%

Phycocyanobilin 藻青素；藻蓝素

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